TY - JOUR
T1 - Calcipotriol toxicity in a dog
AU - Fan, T. M.
AU - Simpson, K. W.
AU - Trasti, S.
AU - Birnbaum, N.
AU - Center, S. A.
AU - Yeager, A.
PY - 1998/12
Y1 - 1998/12
N2 - A six-month-old Labrador retriever was presented for investigation of acute polyuria, polydipsia and haematemesis six hours following ingestion of a tube of the topical antipsoriatic vitamin D analogue, calcipotriol. Transient hypercalcaemia, azotaemia, proteinuria, thrombocytopenia and ventricular arrhythmias ensued. Abdominal ultrasonography and echocardiography revealed evidence of diffuse soft tissue mineralisation. Despite 13 days of intensive supportive care, the dog was euthanased due to continued haematemesis and anorexia. Necropsy confirmed mineralisation and necrosis of multiple organ systems consistent with vitamin D toxicity.
AB - A six-month-old Labrador retriever was presented for investigation of acute polyuria, polydipsia and haematemesis six hours following ingestion of a tube of the topical antipsoriatic vitamin D analogue, calcipotriol. Transient hypercalcaemia, azotaemia, proteinuria, thrombocytopenia and ventricular arrhythmias ensued. Abdominal ultrasonography and echocardiography revealed evidence of diffuse soft tissue mineralisation. Despite 13 days of intensive supportive care, the dog was euthanased due to continued haematemesis and anorexia. Necropsy confirmed mineralisation and necrosis of multiple organ systems consistent with vitamin D toxicity.
UR - http://www.scopus.com/inward/record.url?scp=0032240120&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032240120&partnerID=8YFLogxK
U2 - 10.1111/j.1748-5827.1998.tb03712.x
DO - 10.1111/j.1748-5827.1998.tb03712.x
M3 - Article
C2 - 9888112
AN - SCOPUS:0032240120
VL - 39
SP - 581
EP - 586
JO - Journal of Small Animal Practice
JF - Journal of Small Animal Practice
SN - 0022-4510
IS - 12
ER -