Breakthroughs in Photonics 2013: Quantitative Phase Imaging: Metrology Meets Biology

Taewoo Kim, Renjie Zhou, Lynford L Goddard, Gabriel Popescu

Research output: Contribution to journalReview article

Abstract

Quantitative phase imaging (QPI) is an emerging optical approach that measures the optical path length of a transparent specimen noninvasively. Therefore, it is suitable for studying unstained biological tissues and cells with high sensitivity and resolution. This capability of QPI has fueled itself to grow rapidly as an active field of study for the past two decades. With this trend, QPI has experienced some breakthroughs in methods and applications in the past year. We briefly review some of these breakthroughs in method, including QPI through silicon marker-free phase nanoscopy and white-light diffraction tomography. Furthermore, some of the applications, such as quantitative phase measurement of cell growth and real-time blood testing, are introduced to show the importance and applicability of the field.

Original languageEnglish (US)
Article number0700909
JournalIEEE Photonics Journal
Volume6
Issue number2
DOIs
StatePublished - Apr 1 2014

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Keywords

  • Optical imaging
  • interferometry
  • microscopy
  • phase measurement
  • tomography

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering

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