Breaking Up Is Easy to Do (If You're a DNA Enzyme that Cleaves RNA)

Research output: Contribution to journalReview article


In this issue of Chemistry & Biology, Cruz et al. use in vitro selection to select deoxyribozymes that collectively cleave almost any RNA dinucleotide junction [6]. More remarkable is the finding that the new enzymes are related to the 8-17 deoxyribozyme that cleaves AG dinucleotide junctions.

Original languageEnglish (US)
Pages (from-to)7-8
Number of pages2
JournalChemistry and Biology
Issue number1
StatePublished - Jan 2004


ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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