Branched silica nanostructures oriented by dynamic G-quadruplex transformation

Jinli Zhang, Lin Zheng, Xian Wang, Ying Xiao, Yi Lu, Wei Li

Research output: Contribution to journalArticlepeer-review


Polymorphic G-quadruplexes including stacked G-quartet planes are potentially promising DNA templates beyond Watson-Crick duplexes to construct inorganic nanostructures. In this work, a novel G-rich oligonucleotide that can be modulated from the antiparallel G-quadruplex to multi-stranded supermolecular assemblies was designed. Based on this dynamic G-quadruplex transformation, an interesting leaf-vein silica nanostructure with regular branched intervals was constructed. The G-quadruplex assembly structure was found to play a significant role in the organization of the silica structures.

Original languageEnglish (US)
Pages (from-to)1954-1959
Number of pages6
JournalMaterials Research Bulletin
Issue number12
StatePublished - Dec 2010


  • A. Inorganic compounds
  • A. Nanostructures
  • C. Atomic force microscopy

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Mechanical Engineering
  • Mechanics of Materials


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