Brain activation changes during balance- And attention-demanding tasks in middle- And older-aged adults with multiple sclerosis

Manuel E. Hernandez, Erin O'Donnell, Gioella Chaparro, Roee Holtzer, Meltem Izzetoglu, Brian M. Sandroff, Robert W. Motl

Research output: Contribution to journalArticle

Abstract

Functional near-infrared spectroscopy was used to evaluate prefrontal cortex activation differences between older adults with multiple sclerosis (MS) and healthy older adults (HOA) during the performance of a balance- and attention-demanding motor task. Ten older adults with MS and 12 HOA underwent functional near-infrared spectroscopy recording while talking, virtual beam walking, or virtual beam walking while talking on a self-paced treadmill. The MS group demonstrated smaller increases in prefrontal cortex oxygenation levels than HOA during virtual beam walking while talking than talking tasks. These findings indicate a decreased ability to allocate additional attentional resources in challenging walking conditions among MS compared with HOA. This study is the first to investigate brain activation dynamics during the performance of balance- and attention-demanding motor tasks in persons with MS.

Original languageEnglish (US)
Pages (from-to)498-517
Number of pages20
JournalMotor Control
Volume23
Issue number4
DOIs
StatePublished - Jan 1 2019

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Multiple Sclerosis
Walking
Brain
Near-Infrared Spectroscopy
Prefrontal Cortex

Keywords

  • Cognitive control
  • Divided attention
  • Gait

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Clinical Neurology
  • Physiology (medical)

Cite this

Brain activation changes during balance- And attention-demanding tasks in middle- And older-aged adults with multiple sclerosis. / Hernandez, Manuel E.; O'Donnell, Erin; Chaparro, Gioella; Holtzer, Roee; Izzetoglu, Meltem; Sandroff, Brian M.; Motl, Robert W.

In: Motor Control, Vol. 23, No. 4, 01.01.2019, p. 498-517.

Research output: Contribution to journalArticle

Hernandez, Manuel E. ; O'Donnell, Erin ; Chaparro, Gioella ; Holtzer, Roee ; Izzetoglu, Meltem ; Sandroff, Brian M. ; Motl, Robert W. / Brain activation changes during balance- And attention-demanding tasks in middle- And older-aged adults with multiple sclerosis. In: Motor Control. 2019 ; Vol. 23, No. 4. pp. 498-517.
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