Boundary-enhancement in propagation-based x-ray phase-contrast tomosynthesis improves depth position characterization

Huifeng Guan, Qiaofeng Xu, Alfred B. Garson, Mark A. Anastasio

Research output: Contribution to journalArticlepeer-review


Propagation-based x-ray phase-contrast (PB XPC) tomosynthesis combines the concepts of tomosynthesis and XPC imaging to realize the advantages of both for biological imaging applications. Tomosynthesis permits reductions in acquisition times compared with full-view tomography, while XPC imaging provides the opportunity to resolve weakly absorbing structures. In this note, an investigation of the depth resolving properties of PB XPC tomosynthesis is conducted. The results demonstrate that in-plane structures display strong boundary-enhancement while out-of-plane structures do not. This effect can facilitate the identification of in-plane structures in PB XPC tomosynthesis that could normally not be distinguished from out-of-plane structures in absorption-based tomosynthesis.

Original languageEnglish (US)
Article numberN151
Pages (from-to)N151-N165
JournalPhysics in medicine and biology
Issue number8
StatePublished - Apr 21 2015
Externally publishedYes


  • image reconstruction
  • tomosynthesis
  • x-ray phase-contrast imaging

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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