TY - JOUR
T1 - Bone density and frame size in adult women
T2 - Effects of body size, habitual use, and life history
AU - Lee, Katharine M.N.
AU - Rogers-LaVanne, Mary P.
AU - Galbarczyk, Andrzej
AU - Jasienska, Grazyna
AU - Clancy, Kathryn B.H.
N1 - Funding Information:
American Philosophical Society; Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana‐Champaign; Department of Anthropology, University of Illinois at Urbana‐Champaign; Directorate for Social, Behavioral and Economic Sciences, Grant/Award Numbers: 131740, BCS‐1650839, BCS‐1732117; Division of Graduate Education, Grant/Award Number: DGE‐1144245; Graduate College, University of Illinois at Urbana‐Champaign; Narodowe Centrum Nauki, Grant/Award Number: UMO‐2017/25/B/NZ7/01509; Sigma Xi; Wenner‐Gren Foundation, Grant/Award Numbers: 084918, 089912; National Science Foundation Funding information
Funding Information:
We first and foremost wish to thank the women who participated in this study. We additionally would like to thank Pan Doktor Leszek Pieniązek and Pani Położna Emilia Bulanda for their work on this project. This work would not be possible without all of our research assistants, including (in alphabetical order) Kristina Allen, Vilimira Asenova, Haley Ban, Priya Bhatt, Klaudia Dziewit, Sara Gay, Juliana Georges, Fatima Godfrey, Denise Herrera, Piotr Hutka, Szczepan Jakubowski, Ansley Jones, Jacob Kanthak, Monika Kukla, Karolina Miłkowska, Rachel Mitchell, Agata Orkisz, Kamila Parzonka, Anna Pawińska, Bryana Rivera, Ohm Shukla, Aleksandra Starnawska, Zarin Sultana, Monika Szlachta, Katarzyna Szulc, Aleksandra Wojtarowicz, and Kevin Zavala. We thank Dr. Laura Shackelford for her encouragement and guidance in writing this manuscript. The data collection at the Mogielica Human Ecology Study Site was possible thanks to National Science Centre grant UMO‐2017/25/B/NZ7/01509 (G.J.). This material is based upon work supported by the National Science Foundation under Grant Numbers 1317140, BCS‐1732117, BCS‐1650839, and the Graduate Research Fellowship under Grant Number DGE‐1144245. Any opinion, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation. This work was supported by resources provided by the Biomedical Imaging Center of the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana‐Champaign (UIUC‐BI‐BIC). This work was also supported by Wenner‐Gren #084918, Wenner‐Gren # 089812, The American Philosophical Society Lewis and Clark Fund for Exploration and Field Research, the University of Illinois Department of Anthropology Summer Research Fund, The Beckman Institute Cognitive Science/Artificial Intelligence Award, the University of Illinois Graduate College Dissertation Travel Grant, and Grant‐In‐Aid of Research from Sigma Xi, The Scientific Research Society.
Publisher Copyright:
© 2020 Wiley Periodicals LLC.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/3/1
Y1 - 2021/3/1
N2 - Objective: Bone mineral density (BMD) and frame size are important predictors of future bone health, with smaller frame size and lower BMD associated with higher risk of later fragility fractures. We test the effects of body size, habitual use, and life history on frame size and cortical BMD of the radius and tibia in sample of healthy adult premenopausal women. Methods: We used anthropometry and life history data from 123 women (age 18-46) from rural Poland. Standard techniques were used to measure height, weight, and body fat. Life history factors were recorded using surveys. Grip strength was measured as a proxy for habitual activity, wrist breadth for skeletal frame size. Cortical BMD was measured at the one-third distal point of the radius and mid-point of the tibia using quantitative ultrasound (reported as speed of sound, SoS). Results: Radial SoS was high (mean t-score 3.2 ± 1.6), but tibia SoS was average (mean t-score 0.35 ± 1.17). SoS was not associated with age, although wrist breadth was positively associated with age after adjusting for height. Radius SoS was not associated with measures of body size, habitual use, or life history factors. Wrist breadth was associated with body size (p <.05 for all), lean mass, and grip strength. Tibia SoS was associated with height. Life history factors were not associated with frame size or cortical SoS. Conclusions: Habitual use and overall body size are more strongly associated with frame size and cortical SoS than life history factors in this sample of healthy adult women.
AB - Objective: Bone mineral density (BMD) and frame size are important predictors of future bone health, with smaller frame size and lower BMD associated with higher risk of later fragility fractures. We test the effects of body size, habitual use, and life history on frame size and cortical BMD of the radius and tibia in sample of healthy adult premenopausal women. Methods: We used anthropometry and life history data from 123 women (age 18-46) from rural Poland. Standard techniques were used to measure height, weight, and body fat. Life history factors were recorded using surveys. Grip strength was measured as a proxy for habitual activity, wrist breadth for skeletal frame size. Cortical BMD was measured at the one-third distal point of the radius and mid-point of the tibia using quantitative ultrasound (reported as speed of sound, SoS). Results: Radial SoS was high (mean t-score 3.2 ± 1.6), but tibia SoS was average (mean t-score 0.35 ± 1.17). SoS was not associated with age, although wrist breadth was positively associated with age after adjusting for height. Radius SoS was not associated with measures of body size, habitual use, or life history factors. Wrist breadth was associated with body size (p <.05 for all), lean mass, and grip strength. Tibia SoS was associated with height. Life history factors were not associated with frame size or cortical SoS. Conclusions: Habitual use and overall body size are more strongly associated with frame size and cortical SoS than life history factors in this sample of healthy adult women.
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U2 - 10.1002/ajhb.23502
DO - 10.1002/ajhb.23502
M3 - Article
C2 - 32935454
AN - SCOPUS:85090979613
SN - 1042-0533
VL - 33
JO - American Journal of Human Biology
JF - American Journal of Human Biology
IS - 2
M1 - e23502
ER -