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Bivalent ligands as probes of estrogen receptor action
Kathryn E. Bergmann
, Cynthia H. Wooge
, Kathryn E. Carlson
,
Benita S. Katzenellenbogen
,
John A. Katzenellenbogen
Molecular and Integrative Physiology
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peer-review
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Keyphrases
Estrogen Receptor
100%
Bivalent Ligand
100%
Hexestrol
62%
Reporter Gene
37%
Linker
25%
Monovalent Cations
25%
Progesterone Receptor
25%
Estradiol
25%
Structure-specific
25%
E Series
25%
Estrogen Antagonist
25%
Human Breast Cancer Cells
12%
Transcription Factor
12%
Partial Agonist
12%
Dimerization
12%
Binding Properties
12%
Chinese Hamster Ovary Cells
12%
Monophasic
12%
Gene Construct
12%
Molecular Probe
12%
MCF-7
12%
Competitive Binding
12%
Homodimer
12%
Ethylene Glycol
12%
Functional Role
12%
MCF-7 Cells
12%
Transfection Assay
12%
Binding Curve
12%
Expression Vector
12%
Transcriptional Activation
12%
Receptor Binding Affinity
12%
Estrogen-responsive
12%
Co-agonist
12%
Ligand-based
12%
Vector Encoding
12%
Specific DNA Sequence
12%
Specific Difference
12%
Endogenous Estrogens
12%
Estrogen Response Element
12%
Transient Transfection
12%
Relative Affinity
12%
Chloramphenicol Acetyltransferase
12%
Structural Requirements
12%
Displacement Curve
12%
Competitive Binding Assay
12%
Bioactivity Profile
12%
Nonsteroidal Estrogens
12%
Full Agonist
12%
Gene Transactivation
12%
Inhibitory Ligands
12%
Active Configuration
12%
Biochemistry, Genetics and Molecular Biology
Estrogen Receptor
100%
Reporter Gene
37%
Agonist
25%
Transactivation
25%
Binding Competition
25%
Progesterone Receptor
25%
Estradiol
25%
DNA Sequence
12%
Transcription Factors
12%
Dimerization
12%
Promoter Region
12%
Binding Affinity
12%
Gene Construct
12%
Transcription
12%
Transcription Initiation
12%
Cancer Cell
12%
Expression Vector
12%
Chinese Hamster
12%
Estrogen Responsive Element
12%
Transient Transfection
12%
Chloramphenicol Acetyltransferase
12%
Biological Activity
12%
Ethylene
12%
Receptor Binding
12%
Molecular Probe
12%
Pharmacology, Toxicology and Pharmaceutical Science
Estrogen Receptor
100%
Hexestrol
62%
Progesterone Receptor
25%
Diethylstilbestrol
25%
Antiestrogen
25%
Breast Cancer
12%
Chinese Hamster
12%
Receptor
12%
Transcription Factors
12%
Homodimer
12%
Ethylene Glycol
12%
Partial Agonist
12%
Agonist-Antagonist
12%
Chloramphenicol Acetyltransferase
12%