Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3′-azido, 3′-deoxythymidine: A QSAR investigation

Keyphrases

• Excision 100%
• Bisphosphonates 100%
• HIV-1 Reverse Transcriptase 100%
• 3′-azido-3′-deoxythymidine 100%
• Side Chain 33%
• Biphenyl 33%
• Active Compounds 33%
• Human Immunodeficiency Virus Type 1 (HIV-1) 33%
• Cellular Toxicity 33%
• IC50 Value 33%
• Phosphorolysis 33%
• DNA Primers 33%
• Substituted Phenyl 33%
• Halogen-substituted 33%

Biochemistry, Genetics and Molecular Biology

• Adenosine Triphosphate 100%
• Reverse Transcriptase 100%
• Human Immunodeficiency Virus 1 50%
• IC50 50%