Keyphrases
Bisphosphonates
100%
Trypanosoma Brucei
100%
Comparative Molecular Similarity Indices Analysis (CoMSIA)
100%
Exopolyphosphatase
100%
Vacuolar Pyrophosphatase
100%
Active Compounds
66%
Root Mean Square
66%
Comparative Molecular Field Analysis (CoMFA)
66%
PIC50
66%
Recombinant
33%
Escherichia Coli
33%
IC50
33%
Hydrogen Donor
33%
Mouse Model
33%
Causative Agents
33%
Further Development
33%
R2 Value
33%
Enzyme Inhibition
33%
IC50 Value
33%
Aromatic Ring
33%
Molecular Field
33%
Similarity Index
33%
Mammalian Host
33%
T. Brucei
33%
African Trypanosomiasis
33%
% Protection
33%
Bloodstream Forms
33%
Activity Prediction
33%
CoMFA Model
33%
3D-QSAR
33%
Error Factors
33%
Molecular Similarity
33%
Pharmacology, Toxicology and Pharmaceutical Science
IC50
100%
Bisphosphonic Acid Derivative
100%
Trypanosoma Brucei
100%
Quantitative Structure-Activity Relationship
100%
Inorganic Pyrophosphatase
100%
Infection
50%
Side Effect
50%
Escherichia coli
50%
Mouse Model
50%
Hydrogen Bond
50%
Enzyme Inhibition
50%
African Trypanosomiasis
50%
Biochemistry, Genetics and Molecular Biology
Comparative Molecular Field Analysis
100%
Trypanosoma Brucei
100%
Comparative Molecular Similarity Indices Analysis
100%
Pyrophosphatase
100%
Inorganic Pyrophosphatase
100%
IC50
66%
Hydrogen Bond
33%
Escherichia coli
33%
Mouse Model
33%
Enzyme Inhibition
33%
Three Dimensional Quantitative Structure Activity Relationship
33%
Medicine and Dentistry
IC50
100%
Bisphosphonate
100%
Inorganic Pyrophosphatase
100%
Trypanosoma Brucei
100%
Infection
50%
Escherichia coli
50%
Side Effect
50%
Enzyme Inhibition
50%
African Trypanosomiasis
50%
Immunology and Microbiology
Trypanosoma Brucei
100%
Comparative Molecular Similarity Indices Analysis
100%
Comparative Molecular Field Analysis
100%
IC50
66%
Mouse Model
33%
Escherichia coli
33%
Hydrogen Bond
33%
Enzyme Inhibition
33%
Three Dimensional Quantitative Structure Activity Relationship
33%