Bioprocessing and technoeconomic feasibility analysis of simultaneous production of D-psicose and ethanol using engineered yeast strain KAM-2GD

Ankita Juneja, Guochang Zhang, Yong-Su Jin, Vijay Singh

Research output: Contribution to journalArticle

Abstract

The objective of this study was to analyze the processing and technoeconomic feasibility of coproduction of D-psicose and ethanol in a modified dry grind ethanol process. The yeast strain was constructed by expressing D-psicose 3-epimerases (DPE) in Sachharomyces cerevisiae. The strain was capable of converting D-fructose to D-psicose at 55 °C with a conversion efficiency of 26.6%. A comprehensive process model for modified dry grind ethanol plant with 396,000 MT/yr corn processing capacity was developed using SuperPro Designer. Predicted ethanol and D-psicose yields were 390.4 L and 75.3 kg per MT of corn, with total annual production of 154.6 million L and 29,835 MT respectively. The capital investment for the plant was estimated as 150.3 million USD with total operating cost of 85.2 million USD/yr. The unit production cost and minimum selling price of D-psicose with an internal rate of return of 15% were calculated as $0.43/kg and $1.29/kg respectively.

Original languageEnglish (US)
Pages (from-to)27-34
Number of pages8
JournalBioresource Technology
Volume275
DOIs
StatePublished - Mar 2019

Fingerprint

Yeast
yeast
ethanol
Ethanol
maize
Fructose
Racemases and Epimerases
production cost
Processing
Operating costs
Conversion efficiency
Sales
psicose
analysis
cost
Costs

Keywords

  • Bioprocessing
  • Corn ethanol
  • D-psicose
  • Rare sugar
  • Technoeconomic model

ASJC Scopus subject areas

  • Bioengineering
  • Environmental Engineering
  • Renewable Energy, Sustainability and the Environment
  • Waste Management and Disposal

Cite this

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title = "Bioprocessing and technoeconomic feasibility analysis of simultaneous production of D-psicose and ethanol using engineered yeast strain KAM-2GD",
abstract = "The objective of this study was to analyze the processing and technoeconomic feasibility of coproduction of D-psicose and ethanol in a modified dry grind ethanol process. The yeast strain was constructed by expressing D-psicose 3-epimerases (DPE) in Sachharomyces cerevisiae. The strain was capable of converting D-fructose to D-psicose at 55 °C with a conversion efficiency of 26.6{\%}. A comprehensive process model for modified dry grind ethanol plant with 396,000 MT/yr corn processing capacity was developed using SuperPro Designer. Predicted ethanol and D-psicose yields were 390.4 L and 75.3 kg per MT of corn, with total annual production of 154.6 million L and 29,835 MT respectively. The capital investment for the plant was estimated as 150.3 million USD with total operating cost of 85.2 million USD/yr. The unit production cost and minimum selling price of D-psicose with an internal rate of return of 15{\%} were calculated as $0.43/kg and $1.29/kg respectively.",
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author = "Ankita Juneja and Guochang Zhang and Yong-Su Jin and Vijay Singh",
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AU - Singh, Vijay

PY - 2019/3

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N2 - The objective of this study was to analyze the processing and technoeconomic feasibility of coproduction of D-psicose and ethanol in a modified dry grind ethanol process. The yeast strain was constructed by expressing D-psicose 3-epimerases (DPE) in Sachharomyces cerevisiae. The strain was capable of converting D-fructose to D-psicose at 55 °C with a conversion efficiency of 26.6%. A comprehensive process model for modified dry grind ethanol plant with 396,000 MT/yr corn processing capacity was developed using SuperPro Designer. Predicted ethanol and D-psicose yields were 390.4 L and 75.3 kg per MT of corn, with total annual production of 154.6 million L and 29,835 MT respectively. The capital investment for the plant was estimated as 150.3 million USD with total operating cost of 85.2 million USD/yr. The unit production cost and minimum selling price of D-psicose with an internal rate of return of 15% were calculated as $0.43/kg and $1.29/kg respectively.

AB - The objective of this study was to analyze the processing and technoeconomic feasibility of coproduction of D-psicose and ethanol in a modified dry grind ethanol process. The yeast strain was constructed by expressing D-psicose 3-epimerases (DPE) in Sachharomyces cerevisiae. The strain was capable of converting D-fructose to D-psicose at 55 °C with a conversion efficiency of 26.6%. A comprehensive process model for modified dry grind ethanol plant with 396,000 MT/yr corn processing capacity was developed using SuperPro Designer. Predicted ethanol and D-psicose yields were 390.4 L and 75.3 kg per MT of corn, with total annual production of 154.6 million L and 29,835 MT respectively. The capital investment for the plant was estimated as 150.3 million USD with total operating cost of 85.2 million USD/yr. The unit production cost and minimum selling price of D-psicose with an internal rate of return of 15% were calculated as $0.43/kg and $1.29/kg respectively.

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