Biomimetic surface engineering of lanthanide-doped upconversion nanoparticles as versatile bioprobes

Le Le Li, Ruobing Zhang, Leilei Yin, Kezhi Zheng, Weiping Qin, Paul R. Selvin, Yi Lu

Research output: Contribution to journalArticle

Abstract

Coat of lipids: Water-dispersible and functionalizable upconverting nanoparticles (UCNPs) for selective imaging of live cancer cells were synthesized. The synthetic approach involves coating the surface of the UCNPs with a monolayer of phospholipids that contain different functional groups (see picture), thus allowing for conjugation of many molecules for applications in fields such as bioinspired nanoassembly, biosensing, and biomedicine.

Original languageEnglish (US)
Pages (from-to)6121-6125
Number of pages5
JournalAngewandte Chemie - International Edition
Volume51
Issue number25
DOIs
StatePublished - Jun 18 2012

Keywords

  • imaging agents
  • lanthanides
  • luminescence
  • nanoparticles
  • phospholipids

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

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