Biomedical nanotechnology for molecular imaging, profiling, and drug targeting

Gloria J. Kim; Ruth M. O'Regan; Shuming Nie

doi:10.1109/iembs.2005.1616513

Biomedical nanotechnology for molecular imaging, profiling, and drug targeting

Gloria J. Kim, Ruth M. O'Regan, Shuming Nie

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Nanometer-sized particles have novel optical, electronic, and structural properties that are not available from either individual molecules or bulk solids. When linked with tumor targeting ligands such as monoclonal antibodies, these nanoparticles can be used to target tumor antigens (biomarkers) as well as tumor vasculatures with high affinity and specificity. In the "mesoscopic" size range of 10-100 nm (diameter), nanoparticles also have more surface areas and functional groups that can be linked to multiple diagnostic (e.g., optical, radioisotopic, or magnetic) and therapeutic (e.g., anticancer) agents. In this article, we briefly discuss the use of bioconjugated nanoparticles for delivery and targeting of anticancer drugs.

Original language	English (US)
Title of host publication	Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	714-716
Number of pages	3
ISBN (Print)	0780387406, 9780780387409
DOIs	https://doi.org/10.1109/iembs.2005.1616513
State	Published - 2005
Externally published	Yes
Event	2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai, China Duration: Sep 1 2005 → Sep 4 2005

Publication series

Name	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume	7 VOLS
ISSN (Print)	0589-1019

Other

Other	2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Country/Territory	China
City	Shanghai
Period	9/1/05 → 9/4/05

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Online availability

10.1109/iembs.2005.1616513

Library availability

Discover UIUC Full Text

Cite this

Kim, G. J., O'Regan, R. M., & Nie, S. (2005). Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. In Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 (pp. 714-716). Article 1616513 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 7 VOLS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/iembs.2005.1616513

Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. / Kim, Gloria J.; O'Regan, Ruth M.; Nie, Shuming.
Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005. Institute of Electrical and Electronics Engineers Inc., 2005. p. 714-716 1616513 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 7 VOLS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kim, GJ, O'Regan, RM & Nie, S 2005, Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. in Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005., 1616513, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 7 VOLS, Institute of Electrical and Electronics Engineers Inc., pp. 714-716, 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005, Shanghai, China, 9/1/05. https://doi.org/10.1109/iembs.2005.1616513

Kim GJ, O'Regan RM, Nie S. Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. In Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005. Institute of Electrical and Electronics Engineers Inc. 2005. p. 714-716. 1616513. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). doi: 10.1109/iembs.2005.1616513

Kim, Gloria J. ; O'Regan, Ruth M. ; Nie, Shuming. / Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005. Institute of Electrical and Electronics Engineers Inc., 2005. pp. 714-716 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings).

@inproceedings{82f3e8f8c7e943dbad99341eb3e8783f,

title = "Biomedical nanotechnology for molecular imaging, profiling, and drug targeting",

abstract = "Nanometer-sized particles have novel optical, electronic, and structural properties that are not available from either individual molecules or bulk solids. When linked with tumor targeting ligands such as monoclonal antibodies, these nanoparticles can be used to target tumor antigens (biomarkers) as well as tumor vasculatures with high affinity and specificity. In the {"}mesoscopic{"} size range of 10-100 nm (diameter), nanoparticles also have more surface areas and functional groups that can be linked to multiple diagnostic (e.g., optical, radioisotopic, or magnetic) and therapeutic (e.g., anticancer) agents. In this article, we briefly discuss the use of bioconjugated nanoparticles for delivery and targeting of anticancer drugs.",

author = "Kim, {Gloria J.} and O'Regan, {Ruth M.} and Shuming Nie",

year = "2005",

doi = "10.1109/iembs.2005.1616513",

language = "English (US)",

isbn = "0780387406",

series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "714--716",

booktitle = "Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005",

address = "United States",

note = "2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 ; Conference date: 01-09-2005 Through 04-09-2005",

}

TY - GEN

T1 - Biomedical nanotechnology for molecular imaging, profiling, and drug targeting

AU - Kim, Gloria J.

AU - O'Regan, Ruth M.

AU - Nie, Shuming

PY - 2005

Y1 - 2005

N2 - Nanometer-sized particles have novel optical, electronic, and structural properties that are not available from either individual molecules or bulk solids. When linked with tumor targeting ligands such as monoclonal antibodies, these nanoparticles can be used to target tumor antigens (biomarkers) as well as tumor vasculatures with high affinity and specificity. In the "mesoscopic" size range of 10-100 nm (diameter), nanoparticles also have more surface areas and functional groups that can be linked to multiple diagnostic (e.g., optical, radioisotopic, or magnetic) and therapeutic (e.g., anticancer) agents. In this article, we briefly discuss the use of bioconjugated nanoparticles for delivery and targeting of anticancer drugs.

AB - Nanometer-sized particles have novel optical, electronic, and structural properties that are not available from either individual molecules or bulk solids. When linked with tumor targeting ligands such as monoclonal antibodies, these nanoparticles can be used to target tumor antigens (biomarkers) as well as tumor vasculatures with high affinity and specificity. In the "mesoscopic" size range of 10-100 nm (diameter), nanoparticles also have more surface areas and functional groups that can be linked to multiple diagnostic (e.g., optical, radioisotopic, or magnetic) and therapeutic (e.g., anticancer) agents. In this article, we briefly discuss the use of bioconjugated nanoparticles for delivery and targeting of anticancer drugs.

UR - http://www.scopus.com/inward/record.url?scp=33846930871&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846930871&partnerID=8YFLogxK

U2 - 10.1109/iembs.2005.1616513

DO - 10.1109/iembs.2005.1616513

M3 - Conference contribution

AN - SCOPUS:33846930871

SN - 0780387406

SN - 9780780387409

T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

SP - 714

EP - 716

BT - Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005

Y2 - 1 September 2005 through 4 September 2005

ER -

Biomedical nanotechnology for molecular imaging, profiling, and drug targeting

Abstract

Publication series

Other

ASJC Scopus subject areas

Online availability

Library availability

Related links

Fingerprint

Cite this