Bioinformatic and reactivity-based discovery of linaridins

Keyphrases

• Bioinformatics 100%
• Reaction Screening 100%
• Amino Acids 66%
• Natural Products 66%
• Biosynthetic Gene Clusters 66%
• RiPPs 66%
• Precursor Sequence 33%
• Electrophile 33%
• Streptomyces 33%
• Unique Genes 33%
• Gene Architecture 33%
• Modified Peptide 33%
• Threonine 33%
• Natural Product Discovery 33%
• α,β-unsaturated Carbonyl Compounds 33%
• Thiol-functionalized 33%
• Genome Mining 33%
• Ribosomally Synthesized 33%
• Dehydrobutyrine 33%
• Nucleophilic 1,4-addition 33%
• Mining Tools 33%
• NCBI Database 33%
• Functionalised Probes 33%
• Organic Functional Groups 33%
• Streptomyces Noursei 33%
• Scoring Module 33%

Biochemistry, Genetics and Molecular Biology

• Amino Acids 100%
• Gene Cluster 100%
• Streptomyces 100%
• Precursor 50%
• Thiol 50%
• Nucleophilicity 50%
• Threonine 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Natural Product 100%
• Amino Acid 66%
• Streptomyces 66%
• Thiol 33%
• Functional Groups 33%
• Electrophile 33%
• Threonine 33%