Biochemical review: Coe-alginate impression techniques

The authors have presented Coe-alginate as an impression material for the reproduction of foot models. They have used this technique to modify a moldable Plastazote shoe for patients who underwent a first ray amputation because of osteomyelitis. The shoe was needed to keep pressure off of the second digit, which was displaced dorsally, and to accommodate the amputation defect. Accurate models of hands and feet can be made for educational and instructional purposes. Their use as an example of rheumatoid arthritis has been demonstrated. In addition to the uses described in this paper, a complete foot model produced by this technique could represent an accurate three dimensional template for determining major surgical reconstructive procedures. The authors are involved in investigating its application for clinical use. Further studies involving the use of a derivative of this compound, Sorbsan, for treating open wounds and ulcers have been described.