Biochemical and biophysical understanding of metal ion selectivity of DNAzymes

Kevin Hwang, Parisa Hosseinzadeh, Yi Lu

Research output: Contribution to journalReview article

Abstract

This review summarizes research on the metal-binding properties of catalytic DNAzymes, towards the goal of understanding the structural properties leading to metal ion specificity. Progress made and insight gained from a range of biochemical and biophysical techniques are covered, and promising directions for future investigations are discussed.

Original languageEnglish (US)
Pages (from-to)12-24
Number of pages13
JournalInorganica Chimica Acta
Volume452
DOIs
StatePublished - Jan 1 2016

Fingerprint

Catalytic DNA
Metal ions
Structural properties
metal ions
selectivity
Metals
metals
Direction compound

Keywords

  • Catalytic DNA
  • Deoxyribozymes
  • Metal ion selectivity
  • Metal sensors
  • Metalloenzymes
  • Metal–nucleic acid interactions

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

Cite this

Biochemical and biophysical understanding of metal ion selectivity of DNAzymes. / Hwang, Kevin; Hosseinzadeh, Parisa; Lu, Yi.

In: Inorganica Chimica Acta, Vol. 452, 01.01.2016, p. 12-24.

Research output: Contribution to journalReview article

Hwang, Kevin ; Hosseinzadeh, Parisa ; Lu, Yi. / Biochemical and biophysical understanding of metal ion selectivity of DNAzymes. In: Inorganica Chimica Acta. 2016 ; Vol. 452. pp. 12-24.
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