@article{e9dd2ee44c8146308aa2bdd8d925ae3d,
title = "Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care",
abstract = "Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.",
author = "Chung, {Ha Uk} and Kim, {Bong Hoon} and Lee, {Jong Yoon} and Jungyup Lee and Zhaoqian Xie and Ibler, {Erin M.} and Lee, {Kun Hyuck} and Anthony Banks and Jeong, {Ji Yoon} and Jongwon Kim and Christopher Ogle and Dominic Grande and Yongjoon Yu and Hokyung Jang and Pourya Assem and Dennis Ryu and Kwak, {Jean Won} and Myeong Namkoong and Park, {Jun Bin} and Yechan Lee and Kim, {Do Hoon} and Arin Ryu and Jaeseok Jeong and Kevin You and Bowen Ji and Zhuangjian Liu and Qingze Huo and Xue Feng and Yujun Deng and Yeshou Xu and Jang, {Kyung In} and Jeonghyun Kim and Yihui Zhang and Roozbeh Ghaffari and Rand, {Casey M.} and Molly Schau and Aaron Hamvas and Weese-Mayer, {Debra E.} and Yonggang Huang and Lee, {Seung Min} and Lee, {Chi Hwan} and Shanbhag, {Naresh R.} and Paller, {Amy S.} and Shuai Xu and Rogers, {John A}",
note = "Funding Information: Supported by Bill & Melinda Gates Foundation grants PP1182909 and OPP1193311 (D.E.W.-M., A.H., C.M.R., R.G., S.X., and J.A.R.); the Gerber Foundation (D.E.W.-M., A.H., C.M.R., R.G., and J.A.R.); the Friends of Prentice Foundation (A.S.P., S.X., and J.A.R.); RIE2020 AME Programmatic Grant A18A1b0045 funded by A*STAR-SERC, Singapore (Z.L.); National Natural Science Foundation of China grants 11402134 and 11320101001; National Basic Research Program of China grant 2015CB351900; NSF grants 1534120 and 1635443; and Future Growth Engine Program grant 10079974 funded by the Ministry of Trade, Industry & Energy (MOTIE, South Korea). The materials and engineering efforts were supported by the Center for Bio-Integrated Electronics of the Simpson Querrey Institute at Northwestern University. The in-sensor algorithm development part of this work was supported in part by Systems on Nanoscale Information Fabrics (SONIC), one of the six Semiconductor Research Corporation (SRC) STARnet Centers sponsored by Microelectronics Advanced Research Corporation (MARCO) and Defense Advanced Research Projects Agency (DARPA). This work utilized Northwestern University Micro/Nano Fabrication Facility (NUFAB), which is partially supported by Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the Materials Research Science and Engineering Center (DMR-1720139), the State of Illinois, and Northwestern University. We also acknowledge the Beckman Institute, CAMI, MRL, and NUANCE facilities. This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. This license does not apply to figures/photos/artwork or other content included in the article that is credited to a third party; obtain authorization from the rights holder before using such material. Publisher Copyright: {\textcopyright} 2019 The Authors, some rights reserved. All rights reserved.",
year = "2019",
doi = "10.1126/science.aau0780",
language = "English (US)",
volume = "363",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "6430",
}