Benefits of Exercise Training in Multiple Sclerosis

Robert W. Motl, Brian M. Sandroff

Research output: Contribution to journalReview article


Exercise training represents a behavioral approach for safely managing many of the functional, symptomatic, and quality of life consequences of multiple sclerosis (MS). This topical review paper summarizes evidence from literature reviews and meta-analyses, supplemented by recent individual studies, indicating that exercise training can yield small but important improvements in walking, balance, cognition, fatigue, depression, and quality of life in MS. The paper highlights limitations of research on exercise training and its consequences and future research directions and provides an overview for promotion of exercise training in MS based on recent prescriptive guidelines. Collectively, the evidence for the benefits of exercise training in MS suggests that the time is ripe for the promotion of exercise by healthcare providers, particularly neurologists as a central part of the clinical care and management of MS patients.

Original languageEnglish (US)
Article number62
Pages (from-to)1-9
Number of pages9
JournalCurrent Neurology and Neuroscience Reports
Issue number9
StatePublished - Sep 1 2015


  • Exercise
  • Function
  • Multiple sclerosis
  • Quality of life
  • Symptoms

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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