Bariatric surgery stirs symbionts to counteract diabesity by CA(7)Sting a liver-generated bile acid into the mix

Jason M. Ridlon

doi:10.1016/j.chom.2021.02.011

Bariatric surgery stirs symbionts to counteract diabesity by CA(7)Sting a liver-generated bile acid into the mix

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Abstract

Obesity and diabetes are major health challenges for the 21^st century. Effective treatments affect nutrient signaling along the gut microbiome-bile acid axis. In this issue of Cell, Chaudhari et al. demonstrate that a gut microbial secondary bile acid stimulates hepatic synthesis of a sulfated bile acid with anti-diabetic properties.

Original language	English (US)
Pages (from-to)	320-322
Number of pages	3
Journal	Cell Host and Microbe
Volume	29
Issue number	3
DOIs	https://doi.org/10.1016/j.chom.2021.02.011
State	Published - Mar 10 2021

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

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10.1016/j.chom.2021.02.011

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abstract = "Obesity and diabetes are major health challenges for the 21st century. Effective treatments affect nutrient signaling along the gut microbiome-bile acid axis. In this issue of Cell, Chaudhari et al. demonstrate that a gut microbial secondary bile acid stimulates hepatic synthesis of a sulfated bile acid with anti-diabetic properties.",

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Bariatric surgery stirs symbionts to counteract diabesity by CA(7)Sting a liver-generated bile acid into the mix

Abstract

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