Bactericidal antibiotics and oxidative stress: A radical proposal

Daniel J. Hassett; James A. Imlay

doi:10.1021/cb700232k

Bactericidal antibiotics and oxidative stress: A radical proposal

Research output: Contribution to journal › Article › peer-review

Abstract

A recent publication suggests that many antibiotics exert their bactericidal effects via the production of hydroxyl radicals, regardless of their molecular targets. This proposal represents an abrupt departure from conventional models, land it will attract further experimental tests.

Original language	English (US)
Pages (from-to)	708-710
Number of pages	3
Journal	ACS chemical biology
Volume	2
Issue number	11
DOIs	https://doi.org/10.1021/cb700232k
State	Published - Nov 2007

ASJC Scopus subject areas

Biochemistry
Molecular Medicine

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10.1021/cb700232k

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abstract = "A recent publication suggests that many antibiotics exert their bactericidal effects via the production of hydroxyl radicals, regardless of their molecular targets. This proposal represents an abrupt departure from conventional models, land it will attract further experimental tests.",

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Bactericidal antibiotics and oxidative stress: A radical proposal

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