Avant Garde Fatty Acid Synthesis by Trypanosomes

John E. Cronan

doi:10.1016/j.cell.2006.08.001

Avant Garde Fatty Acid Synthesis by Trypanosomes

Research output: Contribution to journal › Short survey › peer-review

Abstract

In this issue of Cell, Lee et al. (2006) report that the parasite Trypanosoma brucei synthesizes fatty acids in an unconventional way. T. brucei and two other trypanosomes use enzymes called elongases to synthesize myristate, a fourteen carbon (C14) fatty acid essential for pathogenesis. This is an unexpected finding as these enzymes were thought only to elongate already long (C16 or C18) acyl chains.

Original language	English (US)
Pages (from-to)	641-643
Number of pages	3
Journal	Cell
Volume	126
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2006.08.001
State	Published - Aug 25 2006

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Online availability

10.1016/j.cell.2006.08.001

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abstract = "In this issue of Cell, Lee et al. (2006) report that the parasite Trypanosoma brucei synthesizes fatty acids in an unconventional way. T. brucei and two other trypanosomes use enzymes called elongases to synthesize myristate, a fourteen carbon (C14) fatty acid essential for pathogenesis. This is an unexpected finding as these enzymes were thought only to elongate already long (C16 or C18) acyl chains.",

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AB - In this issue of Cell, Lee et al. (2006) report that the parasite Trypanosoma brucei synthesizes fatty acids in an unconventional way. T. brucei and two other trypanosomes use enzymes called elongases to synthesize myristate, a fourteen carbon (C14) fatty acid essential for pathogenesis. This is an unexpected finding as these enzymes were thought only to elongate already long (C16 or C18) acyl chains.

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JO - Cell

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Avant Garde Fatty Acid Synthesis by Trypanosomes

Abstract

ASJC Scopus subject areas

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