Avant Garde Fatty Acid Synthesis by Trypanosomes

Research output: Contribution to journalShort survey

Abstract

In this issue of Cell, Lee et al. (2006) report that the parasite Trypanosoma brucei synthesizes fatty acids in an unconventional way. T. brucei and two other trypanosomes use enzymes called elongases to synthesize myristate, a fourteen carbon (C14) fatty acid essential for pathogenesis. This is an unexpected finding as these enzymes were thought only to elongate already long (C16 or C18) acyl chains.

Original languageEnglish (US)
Pages (from-to)641-643
Number of pages3
JournalCell
Volume126
Issue number4
DOIs
StatePublished - Aug 25 2006

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Trypanosoma brucei brucei
Trypanosomiasis
Fatty Acids
Essential Fatty Acids
Myristic Acid
Enzymes
Parasites
Carbon

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Avant Garde Fatty Acid Synthesis by Trypanosomes. / Cronan, John E.

In: Cell, Vol. 126, No. 4, 25.08.2006, p. 641-643.

Research output: Contribution to journalShort survey

Cronan, John E. / Avant Garde Fatty Acid Synthesis by Trypanosomes. In: Cell. 2006 ; Vol. 126, No. 4. pp. 641-643.
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