Avant Garde Fatty Acid Synthesis by Trypanosomes

Research output: Contribution to journalShort surveypeer-review


In this issue of Cell, Lee et al. (2006) report that the parasite Trypanosoma brucei synthesizes fatty acids in an unconventional way. T. brucei and two other trypanosomes use enzymes called elongases to synthesize myristate, a fourteen carbon (C14) fatty acid essential for pathogenesis. This is an unexpected finding as these enzymes were thought only to elongate already long (C16 or C18) acyl chains.

Original languageEnglish (US)
Pages (from-to)641-643
Number of pages3
Issue number4
StatePublished - Aug 25 2006

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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