Atom-economical route to substituted pyridines via a scandium imide

Benjamin F. Wicker, Jennifer Scott, Alison R. Fout, Maren Pink, Daniel J. Mindiola

Research output: Contribution to journalArticlepeer-review


Taking advantage of a tautomerization process between (PNP)Sc - N(DIPP)(NC5H5) (PNP = N[2-P(CHMe2) 2-4-methylphenyl]2-, DIPP = 2,6-iPr 2C6H3) and (PNP)Sc(NH(DIPP))(η2- NC5H4) (1), we demonstrate in this work that pyridine can be both activated and functionalized with isonitriles (in one case catalytically) to ultimately afford mono- and bis-imino-substituted pyridines. Several intermediates in the cycle have been isolated and characterized.

Original languageEnglish (US)
Pages (from-to)2453-2456
Number of pages4
Issue number9
StatePublished - May 9 2011
Externally publishedYes

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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