Asymmetric Carboalkoxyalkylidenation with a Chiral Horner–Wadsworth–Emmons Reagent

Scott E. Denmark, Isaac Rivera

Research output: Contribution to journalArticle

Abstract

The asymmetric carboalkoxyalkylidenation of 4-substituted cyclohexanones was effected by the use of chirally modified Horner–Wadsworth–Emmons (HWE) reagents in good yields (78–82%) as well as high levels of enantioselectivity (78–86% ee).

Original languageEnglish (US)
Pages (from-to)6887-6889
Number of pages3
JournalJournal of Organic Chemistry
Volume59
Issue number23
DOIs
StatePublished - Nov 1 1994

ASJC Scopus subject areas

  • Organic Chemistry

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