Asymmetric Carboalkoxyalkylidenation with a Chiral Horner–Wadsworth–Emmons Reagent

Scott E. Denmark, Isaac Rivera

Research output: Contribution to journalArticle

Abstract

The asymmetric carboalkoxyalkylidenation of 4-substituted cyclohexanones was effected by the use of chirally modified Horner–Wadsworth–Emmons (HWE) reagents in good yields (78–82%) as well as high levels of enantioselectivity (78–86% ee).

Original languageEnglish (US)
Pages (from-to)6887-6889
Number of pages3
JournalJournal of Organic Chemistry
Volume59
Issue number23
DOIs
StatePublished - Nov 1 1994

Fingerprint

Cyclohexanones
Enantioselectivity

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Asymmetric Carboalkoxyalkylidenation with a Chiral Horner–Wadsworth–Emmons Reagent. / Denmark, Scott E.; Rivera, Isaac.

In: Journal of Organic Chemistry, Vol. 59, No. 23, 01.11.1994, p. 6887-6889.

Research output: Contribution to journalArticle

@article{e020a1e34a5a49b1b53377c52affe2ee,
title = "Asymmetric Carboalkoxyalkylidenation with a Chiral Horner–Wadsworth–Emmons Reagent",
abstract = "The asymmetric carboalkoxyalkylidenation of 4-substituted cyclohexanones was effected by the use of chirally modified Horner–Wadsworth–Emmons (HWE) reagents in good yields (78–82{\%}) as well as high levels of enantioselectivity (78–86{\%} ee).",
author = "Denmark, {Scott E.} and Isaac Rivera",
year = "1994",
month = "11",
day = "1",
doi = "10.1021/jo00102a005",
language = "English (US)",
volume = "59",
pages = "6887--6889",
journal = "Journal of Organic Chemistry",
issn = "0022-3263",
publisher = "American Chemical Society",
number = "23",

}

TY - JOUR

T1 - Asymmetric Carboalkoxyalkylidenation with a Chiral Horner–Wadsworth–Emmons Reagent

AU - Denmark, Scott E.

AU - Rivera, Isaac

PY - 1994/11/1

Y1 - 1994/11/1

N2 - The asymmetric carboalkoxyalkylidenation of 4-substituted cyclohexanones was effected by the use of chirally modified Horner–Wadsworth–Emmons (HWE) reagents in good yields (78–82%) as well as high levels of enantioselectivity (78–86% ee).

AB - The asymmetric carboalkoxyalkylidenation of 4-substituted cyclohexanones was effected by the use of chirally modified Horner–Wadsworth–Emmons (HWE) reagents in good yields (78–82%) as well as high levels of enantioselectivity (78–86% ee).

UR - http://www.scopus.com/inward/record.url?scp=0001569397&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0001569397&partnerID=8YFLogxK

U2 - 10.1021/jo00102a005

DO - 10.1021/jo00102a005

M3 - Article

AN - SCOPUS:0001569397

VL - 59

SP - 6887

EP - 6889

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

SN - 0022-3263

IS - 23

ER -