Association of ADIPOQ, OLR1 and PPARGC1A gene polymorphisms with growth and carcass traits in Nelore cattle

Patrícia D.da S. Fonseca; Fábio R.P. de Souza; Gregório M.F. De Camargo; Fernanda M.M. Gil; Diercles F. Cardoso; Larissa Zetouni; Camila U. Braz; Arione A. Boligon; Renata H. Branco; Lucia G. de Albuquerque; Maria E.Z. Mercadante; Humberto Tonhati

doi:10.1016/j.mgene.2015.02.001

Association of ADIPOQ, OLR1 and PPARGC1A gene polymorphisms with growth and carcass traits in Nelore cattle

Patrícia D.da S. Fonseca
, Fábio R.P. de Souza
, Gregório M.F. De Camargo
, Fernanda M.M. Gil
, Diercles F. Cardoso
, Larissa Zetouni
, Camila U. Braz
, Arione A. Boligon
, Renata H. Branco
, Lucia G. de Albuquerque
, Maria E.Z. Mercadante
, Humberto Tonhati

Research output: Contribution to journal › Article › peer-review

Abstract

In beef cattle farming, growth and carcass traits are important for genetic breeding programs. Molecular markers can be used to assist selection and increase genetic gain. The ADIPOQ, OLR1 and PPARGC1A genes are involved in lipid synthesis and fat accumulation in adipose tissue. The objective of this study was to identify polymorphisms in these genes and to assess the association with growth and carcass traits in Nelore cattle. A total of 639 animals were genotyped by PCR-RFLP for rs208549452, rs109019599 and rs109163366 in ADIPOQ, OLR1 and PPARGC1A gene, respectively. We analyzed the association of SNPs identified with birth weight, weaning weight, female yearling weight, female hip height, male yearling weight, male hip height, loin eye area, rump fat thickness, and backfat thickness. The OLR1 marker was associated with rump fat thickness and weaning weight (P. <. 0.05) and the PPARGC1 marker was associated with female yearling weight.

Original language	English (US)
Pages (from-to)	1-7
Number of pages	7
Journal	Meta Gene
Volume	4
DOIs	https://doi.org/10.1016/j.mgene.2015.02.001
State	Published - Jun 1 2015
Externally published	Yes

Keywords

Bos taurus indicus
Molecular markers
PCR-RFLP
SNP

ASJC Scopus subject areas

Genetics
Genetics(clinical)

Online availability

10.1016/j.mgene.2015.02.001

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Fonseca, P. D. D. S., de Souza, F. R. P., De Camargo, G. M. F., Gil, F. M. M., Cardoso, D. F., Zetouni, L., Braz, C. U., Boligon, A. A., Branco, R. H., de Albuquerque, L. G., Mercadante, M. E. Z., & Tonhati, H. (2015). Association of ADIPOQ, OLR1 and PPARGC1A gene polymorphisms with growth and carcass traits in Nelore cattle. Meta Gene, 4, 1-7. https://doi.org/10.1016/j.mgene.2015.02.001

@article{63793d8a86054b728cfb261dc95bb8d5,

title = "Association of ADIPOQ, OLR1 and PPARGC1A gene polymorphisms with growth and carcass traits in Nelore cattle",

abstract = "In beef cattle farming, growth and carcass traits are important for genetic breeding programs. Molecular markers can be used to assist selection and increase genetic gain. The ADIPOQ, OLR1 and PPARGC1A genes are involved in lipid synthesis and fat accumulation in adipose tissue. The objective of this study was to identify polymorphisms in these genes and to assess the association with growth and carcass traits in Nelore cattle. A total of 639 animals were genotyped by PCR-RFLP for rs208549452, rs109019599 and rs109163366 in ADIPOQ, OLR1 and PPARGC1A gene, respectively. We analyzed the association of SNPs identified with birth weight, weaning weight, female yearling weight, female hip height, male yearling weight, male hip height, loin eye area, rump fat thickness, and backfat thickness. The OLR1 marker was associated with rump fat thickness and weaning weight (P. <. 0.05) and the PPARGC1 marker was associated with female yearling weight.",

keywords = "Bos taurus indicus, Molecular markers, PCR-RFLP, SNP",

author = "Fonseca, \{Patr{\'i}cia D.da S.\} and \{de Souza\}, \{F{\'a}bio R.P.\} and \{De Camargo\}, \{Greg{\'o}rio M.F.\} and Gil, \{Fernanda M.M.\} and Cardoso, \{Diercles F.\} and Larissa Zetouni and Braz, \{Camila U.\} and Boligon, \{Arione A.\} and Branco, \{Renata H.\} and \{de Albuquerque\}, \{Lucia G.\} and Mercadante, \{Maria E.Z.\} and Humberto Tonhati",

note = "This work was supported by Funda{\c c}{\~a}o de Amparo {\`a} Pesquisa do Estado de S{\~a}o Paulo ( 2009/16118-5 ). We are indebted to the Instituto de Zootecnia for providing the cattle blood samples and the data set used in this study.",

year = "2015",

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doi = "10.1016/j.mgene.2015.02.001",

language = "English (US)",

volume = "4",

pages = "1--7",

journal = "Meta Gene",

issn = "2214-5400",

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T1 - Association of ADIPOQ, OLR1 and PPARGC1A gene polymorphisms with growth and carcass traits in Nelore cattle

AU - Fonseca, Patrícia D.da S.

AU - de Souza, Fábio R.P.

AU - De Camargo, Gregório M.F.

AU - Gil, Fernanda M.M.

AU - Cardoso, Diercles F.

AU - Zetouni, Larissa

AU - Braz, Camila U.

AU - Boligon, Arione A.

AU - Branco, Renata H.

AU - de Albuquerque, Lucia G.

AU - Mercadante, Maria E.Z.

AU - Tonhati, Humberto

N1 - This work was supported by Fundação de Amparo à Pesquisa do Estado de São Paulo ( 2009/16118-5 ). We are indebted to the Instituto de Zootecnia for providing the cattle blood samples and the data set used in this study.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - In beef cattle farming, growth and carcass traits are important for genetic breeding programs. Molecular markers can be used to assist selection and increase genetic gain. The ADIPOQ, OLR1 and PPARGC1A genes are involved in lipid synthesis and fat accumulation in adipose tissue. The objective of this study was to identify polymorphisms in these genes and to assess the association with growth and carcass traits in Nelore cattle. A total of 639 animals were genotyped by PCR-RFLP for rs208549452, rs109019599 and rs109163366 in ADIPOQ, OLR1 and PPARGC1A gene, respectively. We analyzed the association of SNPs identified with birth weight, weaning weight, female yearling weight, female hip height, male yearling weight, male hip height, loin eye area, rump fat thickness, and backfat thickness. The OLR1 marker was associated with rump fat thickness and weaning weight (P. <. 0.05) and the PPARGC1 marker was associated with female yearling weight.

AB - In beef cattle farming, growth and carcass traits are important for genetic breeding programs. Molecular markers can be used to assist selection and increase genetic gain. The ADIPOQ, OLR1 and PPARGC1A genes are involved in lipid synthesis and fat accumulation in adipose tissue. The objective of this study was to identify polymorphisms in these genes and to assess the association with growth and carcass traits in Nelore cattle. A total of 639 animals were genotyped by PCR-RFLP for rs208549452, rs109019599 and rs109163366 in ADIPOQ, OLR1 and PPARGC1A gene, respectively. We analyzed the association of SNPs identified with birth weight, weaning weight, female yearling weight, female hip height, male yearling weight, male hip height, loin eye area, rump fat thickness, and backfat thickness. The OLR1 marker was associated with rump fat thickness and weaning weight (P. <. 0.05) and the PPARGC1 marker was associated with female yearling weight.

KW - Bos taurus indicus

KW - Molecular markers

KW - PCR-RFLP

KW - SNP

UR - https://www.scopus.com/pages/publications/84929315283

UR - https://www.scopus.com/pages/publications/84929315283#tab=citedBy

U2 - 10.1016/j.mgene.2015.02.001

DO - 10.1016/j.mgene.2015.02.001

M3 - Article

AN - SCOPUS:84929315283

SN - 2214-5400

VL - 4

SP - 1

EP - 7

JO - Meta Gene

JF - Meta Gene

ER -

Association of ADIPOQ, OLR1 and PPARGC1A gene polymorphisms with growth and carcass traits in Nelore cattle

Abstract

Keywords

ASJC Scopus subject areas

Online availability

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