TY - JOUR
T1 - Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients
AU - Cavalcante, Bruno Remigio
AU - Germano-Soares, Antonio H.
AU - Gerage, Aline M.
AU - Leicht, Anthony
AU - Tassitano, Rafael M.
AU - Bortolotti, Henrique
AU - de Mello Franco, Fábio Gazelato
AU - Wolosker, Nelson
AU - Cucato, Gabriel G.
AU - Ritti-Dias, Raphael M.
N1 - Funding Information:
BRC and AHGS were supported by the Coordination for the Improvement of Higher Education Personnel (CAPES – Master scholarship). GGC holds a grant from The National Council for Scientific and Technological Development (CNPq #409707/2016–3). RMRD holds a research productivity fellowship (PQ-A2) granted by CNPq.
Funding Information:
BRC and AHGS were supported by the Coordination for the Improvement of Higher Education Personnel (CAPES ? Master scholarship). GGC holds a grant from The National Council for Scientific and Technological Development (CNPq #409707/2016?3). RMRD holds a research productivity fellowship (PQ-A2) granted by CNPq.
Publisher Copyright:
© 2018 European Society for Vascular Surgery
PY - 2018/5
Y1 - 2018/5
N2 - Objective: To identify the association between objectively measured physical activity and walking capacity with cognitive function in patients with symptomatic peripheral artery disease. Methods: This was an observational, cross sectional study. One hundred and thirty patients (age 67 ± 8 years) were recruited at a tertiary centre specializing in vascular disease. Cognitive function (global, memory, executive function and attention) was evaluated using the Montreal Cognitive Assessment tool. Physical activity levels (total, light, and moderate-vigorous) were obtained using an accelerometer. A 6 min and 4 m walk test were undertaken to assess walking capacity. Crude and covariate adjusted, linear regression analyses confirmed significant associations between physical activity levels and walking capacity with cognitive function. Results: Positive and significant associations were observed between moderate to vigorous physical activity (p =.039) and walking capacity (p =.030) with memory after adjusting for covariates. No significant association was identified between light physical activity and usual gait speed with any cognitive function outcome. Conclusion: Greater memory performance was associated with greater moderate to vigorous physical activity levels and walking capacity in patients with symptomatic peripheral artery disease. Clinical interventions focused on improving moderate to vigorous physical activity levels and walking capacity may provide important therapies to potentially enhance cognitive health in patients with peripheral artery disease.
AB - Objective: To identify the association between objectively measured physical activity and walking capacity with cognitive function in patients with symptomatic peripheral artery disease. Methods: This was an observational, cross sectional study. One hundred and thirty patients (age 67 ± 8 years) were recruited at a tertiary centre specializing in vascular disease. Cognitive function (global, memory, executive function and attention) was evaluated using the Montreal Cognitive Assessment tool. Physical activity levels (total, light, and moderate-vigorous) were obtained using an accelerometer. A 6 min and 4 m walk test were undertaken to assess walking capacity. Crude and covariate adjusted, linear regression analyses confirmed significant associations between physical activity levels and walking capacity with cognitive function. Results: Positive and significant associations were observed between moderate to vigorous physical activity (p =.039) and walking capacity (p =.030) with memory after adjusting for covariates. No significant association was identified between light physical activity and usual gait speed with any cognitive function outcome. Conclusion: Greater memory performance was associated with greater moderate to vigorous physical activity levels and walking capacity in patients with symptomatic peripheral artery disease. Clinical interventions focused on improving moderate to vigorous physical activity levels and walking capacity may provide important therapies to potentially enhance cognitive health in patients with peripheral artery disease.
KW - Cognition
KW - Functional performance
KW - Peripheral arterial disease
KW - Physical activity
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U2 - 10.1016/j.ejvs.2018.02.010
DO - 10.1016/j.ejvs.2018.02.010
M3 - Article
C2 - 29580833
AN - SCOPUS:85044338111
SN - 1078-5884
VL - 55
SP - 672
EP - 678
JO - European Journal of Vascular and Endovascular Surgery
JF - European Journal of Vascular and Endovascular Surgery
IS - 5
ER -