Association between change in physical activity and short-term disability progression in multiple sclerosis

Robert W. Motl, Edward McAuley

Research output: Contribution to journalArticle

Abstract

Objective: This study examined change in physical activity as a behavioral correlate of short-term disability progression in persons with multiple sclerosis over a 6-month period.Design: Panel design.Subjects: The sample included 292 persons with multiple sclerosis.Methods: Participants wore an accelerometer for 7 days as a measure of physical activity and then provided demographics and clinical information and completed the Patient Determined Disease Steps scale as a measure of disability. After a 6-month period, participants provided information about the occurrence of a relapse in the previous 6 months and again wore an accelerometer for 7 days and completed the Patient Determined Disease Steps scale.Results: Panel analysis indicated associations between baseline physical activity and disability (path coefficient =-0.41, p < 0.001) and 6-month change in physical activity and disability progression (path coefficient =-0.09, p = 0.025). Conclusion: Such findings provide preliminary support for a reduction in physical activity as a behavioral correlate, but not necessarily cause, of short-term disability progression in persons with multiple sclerosis.

Original languageEnglish (US)
Pages (from-to)305-310
Number of pages6
JournalJournal of Rehabilitation Medicine
Volume43
Issue number4
DOIs
StatePublished - Mar 2011

Keywords

  • Mobility
  • Neurological disease
  • Rehabilitation

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

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