Association between birthweight, cardiovascular risk factors, and depression in young mexican adults

Luis Adolfo Santos-Calderón, Juan Manuel Vargas-Morales, Omar Sánchez Armáss Capello, Margarita Terán-García, Patricia Elizabeth Cossío-Torres, Marisol Vidal-Batres, Joan D. Fernández-Ballart, Celia Aradillas-García

Research output: Contribution to journalArticlepeer-review


Background: the aim of this study was to investigate the association between birthweight, cardiovascular disease (CVD) risk factors, and depression in young Mexican adults. Methods: birthweight reports, family history of CVD and diabetes-related diseases, anthropometrics, serum lipid profile (total cholesterol [TC], triglycerides [TG], high-density lipoprotein-cholesterol [HDL-C], low-density lipoprotein-cholesterol [LDL-C], and very-low density lipoprotein-cholesterol [VLDL-C]), and depressive symptoms were measured in 778 subjects of the UP-AMIGOS cohort study. To investigate the association between birthweight categories and CVD risk factors and depression, a one-way analysis of variance with post-hoc test was performed of quantitative variables, and c2 test for qualitative variables. Results: mean age was 17.8 years and 469 (60.3 %) of patients were female (n = 469, 60.3 %). The percentage of patients with low birthweight (LBW) was 8.1 % (n = 63), and 3.3 % (n = 26) reported high birthweight (HBW). Young adults with HBW were associated with elevated diastolic blood pressure (DBP), and high weight and body mass index (BMI) when compared to LBW subjects, the difference being statically significant (p < 0.05). Birthweight had no significant association with depression (p > 0.67). Conclusion: the findings from this population-based study revealed a positive relation between birthweight categories and some CVD risk factors. Depression was not related to birthweight.
Original languageEnglish (US)
Pages (from-to)833-838
Number of pages6
JournalNutricion Hospitalaria
Issue number4
StatePublished - 2021


  • Birthweight
  • Cardiovascular risk
  • Depression
  • Mexican population


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