Assessment of a point-of-care lactate monitor in emergency admissions of adult horses to a referral hospital

Brett S. Tennent-Brown, Pamela A. Wilkins, Sue Lindborg, Gail Russell, Raymond C. Boston

Research output: Contribution to journalArticlepeer-review


Background: Blood lactate concentration [LAC] is considered a useful indicator of disease severity in horses. Agreement of point-of-care (POC) lactate monitors with laboratory standards has not been established for clinically abnormal horses. Hypothesis: It was hypothesized that results from a POC lactate monitor would be in agreement with a laboratory-based measurement of [LAC]. Animals: The study included adult horses presented for emergency evaluation. Methods: A prospective observational study was performed. [LAC] was measured with whole blood (AWB) and plasma (APL) by means of a POC monitor (Accutrend) and compared with results from whole blood measured by a laboratory blood gas analyzer (NOVA). Results: Samples from 221 horses were used to compare the 2 lactate measurement techniques. Agreement (ρ ± SE) was closest between APL and NOVA (0.97 ± 0.01); an average observed difference of 0.15 ± 0.89 (mean ± SD) and 95% limits of agreement (LOA) -1.89, 1.59 also were found. Agreement was preserved and 95% LOA further decreased in horses with NOVA [LAC] of <5 mM and PCV <40%. Agreement was modest when testing whole blood samples on the POC monitor with increased 95% LOA. Conclusions and Clinical Importance: Results indicate close agreement between NOVA and the POC monitor when [LAC] was measured with plasma. Results were less consistent at higher [LAC] but sufficiently reliable to follow trends. Although whole blood may be used with the POC monitor to identify clinically important hyperlactatemia, results may be insufficiently reliable to monitor trends.

Original languageEnglish (US)
Pages (from-to)1090-1098
Number of pages9
JournalJournal of veterinary internal medicine
Issue number5
StatePublished - Sep 2007
Externally publishedYes


  • Agreement
  • Critical care
  • Lactatemia

ASJC Scopus subject areas

  • veterinary(all)


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