Abstract
In this work, we proposed a next generation MRI compatible SPECT system, MRC-SPECT-II, based on an artificial compound eye (ACE) gamma camera design inspired by compound eyes often found in small invertebrate. The MRC-SPECT II had a very compact - 6cm detector ring size, but it consisted of 1536 independent micro-pinhole-gamma-camera-elements looking at the object. Each of the micro-camera-elements covered a narrow view angular in the object space. This system design could cover a FOV of 1cm diameter with a very rich angular sampling. Furthermore, the Monte Carlo study showed MRC-SPECT-II could achieve peak geometry efficiency of around 1.5% (as compared to the typical levels of 0.1%-0.01% found in modern pre-clinical SPECT instrumentations), while maintaining a spatial resolution of around 0.5 mm. Compared to the MRC-SPECT-I system that we have developed, the compact MRC-SPECT-II system could sit inside pre-clinical MRI scanner and potentially allowed us to take MRI and SPECT imaging at the same time. Also the dramatic increase in sensitivity could potentially lead to a radical change in how we might employ SPECT imagining in both pre-clinical and (potentially) clinical practice, by offering much lower detection limit and allowing for new imaging procedures that would be difficult to implement with the current generation of SPECT instrumentations.
Original language | English (US) |
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Title of host publication | 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
ISBN (Print) | 9781479905348 |
DOIs | |
State | Published - 2013 |
Event | 2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 - Seoul, Korea, Republic of Duration: Oct 27 2013 → Nov 2 2013 |
Other
Other | 2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 |
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Country/Territory | Korea, Republic of |
City | Seoul |
Period | 10/27/13 → 11/2/13 |
ASJC Scopus subject areas
- Radiation
- Nuclear and High Energy Physics
- Radiology Nuclear Medicine and imaging