Artificial compound-eye gamma camera for MRI compatible SPECT imaging

Xiao Chun Lai, Ling Jian Meng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this work, we proposed a next generation MRI compatible SPECT system, MRC-SPECT-II, based on an artificial compound eye (ACE) gamma camera design inspired by compound eyes often found in small invertebrate. The MRC-SPECT II had a very compact - 6cm detector ring size, but it consisted of 1536 independent micro-pinhole-gamma-camera-elements looking at the object. Each of the micro-camera-elements covered a narrow view angular in the object space. This system design could cover a FOV of 1cm diameter with a very rich angular sampling. Furthermore, the Monte Carlo study showed MRC-SPECT-II could achieve peak geometry efficiency of around 1.5% (as compared to the typical levels of 0.1%-0.01% found in modern pre-clinical SPECT instrumentations), while maintaining a spatial resolution of around 0.5 mm. Compared to the MRC-SPECT-I system that we have developed, the compact MRC-SPECT-II system could sit inside pre-clinical MRI scanner and potentially allowed us to take MRI and SPECT imaging at the same time. Also the dramatic increase in sensitivity could potentially lead to a radical change in how we might employ SPECT imagining in both pre-clinical and (potentially) clinical practice, by offering much lower detection limit and allowing for new imaging procedures that would be difficult to implement with the current generation of SPECT instrumentations.

Original languageEnglish (US)
Title of host publication2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479905348
DOIs
StatePublished - 2013
Event2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 - Seoul, Korea, Republic of
Duration: Oct 27 2013Nov 2 2013

Other

Other2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
CountryKorea, Republic of
CitySeoul
Period10/27/1311/2/13

Fingerprint

Artificial Eye
Gamma Cameras
Single-Photon Emission-Computed Tomography
cameras
invertebrates
pinholes
systems engineering
scanners
spatial resolution
sampling
sensitivity
rings
detectors
geometry
Invertebrates
Limit of Detection

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

Cite this

Lai, X. C., & Meng, L. J. (2013). Artificial compound-eye gamma camera for MRI compatible SPECT imaging. In 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 [6829175] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2013.6829175

Artificial compound-eye gamma camera for MRI compatible SPECT imaging. / Lai, Xiao Chun; Meng, Ling Jian.

2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013. Institute of Electrical and Electronics Engineers Inc., 2013. 6829175.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lai, XC & Meng, LJ 2013, Artificial compound-eye gamma camera for MRI compatible SPECT imaging. in 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013., 6829175, Institute of Electrical and Electronics Engineers Inc., 2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013, Seoul, Korea, Republic of, 10/27/13. https://doi.org/10.1109/NSSMIC.2013.6829175
Lai XC, Meng LJ. Artificial compound-eye gamma camera for MRI compatible SPECT imaging. In 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013. Institute of Electrical and Electronics Engineers Inc. 2013. 6829175 https://doi.org/10.1109/NSSMIC.2013.6829175
Lai, Xiao Chun ; Meng, Ling Jian. / Artificial compound-eye gamma camera for MRI compatible SPECT imaging. 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013. Institute of Electrical and Electronics Engineers Inc., 2013.
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