Aptamer-based origami paper analytical device for electrochemical detection of adenosine

Hong Liu, Yu Xiang, Yi Lu, Richard M. Crooks

Research output: Contribution to journalArticlepeer-review

Abstract

Paper biosensors: An origami sensor is printed on a single piece of paper, folded into a three-dimensional fluidic device, and encapsulated by thermal lamination. Aptamer is trapped in the fluidic channel, where it binds to the target and releases an enzyme to generate a signal. The device is read out using a digital multimeter.

Original languageEnglish (US)
Pages (from-to)6925-6928
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number28
DOIs
StatePublished - Jul 9 2012

Keywords

  • aptamers
  • biosensors
  • current amplification
  • electrochemistry
  • paper fluidic devices

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

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