TY - GEN
T1 - Aperture design for ultra-high resolution SPECT systems for small animal imaging
AU - Fu, Geng
AU - Tan, Jia Wei
AU - Meng, Ling Jian
PY - 2007
Y1 - 2007
N2 - In this paper, we present the results from a design study for an ultra-high resolution SPECT system with various aperture designs. The system uses a recently developed ultra-high resolution gamma camera based on an intensified Electron-multiplying Charge Coupled Device (EMCCD) sensor. It provides an intrinsic spatial resolution of <60um and a high signal-to-noise ratio for imaging the 27-35keV photons emitted by 1-125. The goal of present work is to optimize the multiple-pinhole aperture design for a stationary 4 headed SPECT system. The system is equipped with a variable aperture system that allows a large number of different aperture configurations to be used. In this study, we used the resolution-variance tradeoff as a performance index for selecting appropriate apertures for several imaging scenarios. A large number of apertures were compared with Monte Carlo simulations and experimental measurements.
AB - In this paper, we present the results from a design study for an ultra-high resolution SPECT system with various aperture designs. The system uses a recently developed ultra-high resolution gamma camera based on an intensified Electron-multiplying Charge Coupled Device (EMCCD) sensor. It provides an intrinsic spatial resolution of <60um and a high signal-to-noise ratio for imaging the 27-35keV photons emitted by 1-125. The goal of present work is to optimize the multiple-pinhole aperture design for a stationary 4 headed SPECT system. The system is equipped with a variable aperture system that allows a large number of different aperture configurations to be used. In this study, we used the resolution-variance tradeoff as a performance index for selecting appropriate apertures for several imaging scenarios. A large number of apertures were compared with Monte Carlo simulations and experimental measurements.
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U2 - 10.1109/NSSMIC.2007.4436718
DO - 10.1109/NSSMIC.2007.4436718
M3 - Conference contribution
AN - SCOPUS:48149094390
SN - 1424409233
SN - 9781424409235
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 2785
EP - 2790
BT - 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
T2 - 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Y2 - 27 October 2007 through 3 November 2007
ER -