Aperture design for ultra-high resolution SPECT systems for small animal imaging

Geng Fu, Jia Wei Tan, Ling Jian Meng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we present the results from a design study for an ultra-high resolution SPECT system with various aperture designs. The system uses a recently developed ultra-high resolution gamma camera based on an intensified Electron-multiplying Charge Coupled Device (EMCCD) sensor. It provides an intrinsic spatial resolution of <60um and a high signal-to-noise ratio for imaging the 27-35keV photons emitted by 1-125. The goal of present work is to optimize the multiple-pinhole aperture design for a stationary 4 headed SPECT system. The system is equipped with a variable aperture system that allows a large number of different aperture configurations to be used. In this study, we used the resolution-variance tradeoff as a performance index for selecting appropriate apertures for several imaging scenarios. A large number of apertures were compared with Monte Carlo simulations and experimental measurements.

Original languageEnglish (US)
Title of host publication2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Pages2785-2790
Number of pages6
DOIs
StatePublished - Dec 1 2007
Event2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC - Honolulu, HI, United States
Duration: Oct 27 2007Nov 3 2007

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume4
ISSN (Print)1095-7863

Other

Other2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
CountryUnited States
CityHonolulu, HI
Period10/27/0711/3/07

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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