TY - JOUR
T1 - Antifreeze glycoprotein biosynthesis in antarctic fishes
AU - Hudson, Alan P.
AU - DeVries, Arthur L.
AU - Haschemeyer, Audrey E.V.
N1 - Funding Information:
Acknowled~lements Support for A. P. ttudsorl through the Mina Rees Award for Research m the Natural Science,, and Mathematics of the ('ity University of New York is gratefully acknowledged. (omputations were carried out at the City University Computer ('entre. This investigation was supported b~ National Science Foundation Grants GB-42752. PCM-77-07164 and OPP-74-07917.
PY - 1979
Y1 - 1979
N2 - 1. 1. The synthesis and secretion of antifreeze glycoproteins (AFGP) and other plasma proteins has been examined by 14C-alanine pulse-labelling in the Antarctic cod (Dissostichus mawsoni) at - 1.5°C. 2. 2. Protein synthetic rates (μg/hr per g liver) were estimated to be 130 for intrahepatic proteins, 75 for plasma proteins, and 2 for AFGP polypeptide. 3. 3. Time constants for secretion events have been obtained by kinetic analysis and compared with results in a temperate fish and in mammals.
AB - 1. 1. The synthesis and secretion of antifreeze glycoproteins (AFGP) and other plasma proteins has been examined by 14C-alanine pulse-labelling in the Antarctic cod (Dissostichus mawsoni) at - 1.5°C. 2. 2. Protein synthetic rates (μg/hr per g liver) were estimated to be 130 for intrahepatic proteins, 75 for plasma proteins, and 2 for AFGP polypeptide. 3. 3. Time constants for secretion events have been obtained by kinetic analysis and compared with results in a temperate fish and in mammals.
UR - http://www.scopus.com/inward/record.url?scp=5644302053&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=5644302053&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(79)90308-0
DO - 10.1016/0305-0491(79)90308-0
M3 - Article
AN - SCOPUS:5644302053
SN - 1096-4959
VL - 62
SP - 179
EP - 183
JO - Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
JF - Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
IS - 2
ER -