Anomalous transitions of DODAB using fast scanning liquid calorimetry

Lito P. De La Rama, Liang Hu, Mikhail Y. Efremov, Eric A. Olson, Paul F. Nealey, Mark A. McLean, Stephen G. Sligar, Leslie H. Allen

Research output: Contribution to journalArticle

Abstract

Anomalous melting transitions are observed on dimethyl dioctadecyl ammonium bromide (DODAB) using a fast-scanning liquid calorimeter. A single transition is observed at low scan rates (1 K/min) while up to four peaks are evident at high scan rates (60 K/min). These deconvoluted transitions are signatures of the basic properties of the transition kinetic landscape which are convoluted into a single peak at low scanning rates. The technique is also applied to the proteins Rnase A, Lysozyme and Cytochrome P450. The calorimeter is a glass capillary uniformly coated with Ag, which acts both as the heating element and resistive thermometer.

Original languageEnglish (US)
Pages (from-to)72-76
Number of pages5
JournalThermochimica Acta
Volume522
Issue number1-2
DOIs
StatePublished - Aug 10 2011

Keywords

  • DODAB phase transition
  • Liquid calorimetry
  • Protein calorimetry

ASJC Scopus subject areas

  • Instrumentation
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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  • Cite this

    De La Rama, L. P., Hu, L., Efremov, M. Y., Olson, E. A., Nealey, P. F., McLean, M. A., Sligar, S. G., & Allen, L. H. (2011). Anomalous transitions of DODAB using fast scanning liquid calorimetry. Thermochimica Acta, 522(1-2), 72-76. https://doi.org/10.1016/j.tca.2011.05.033