Anodized/etched and dis treated ti surfaces to promote bone formation

Andrea Mesa, Robinson Montes, Edwin Patiño, Juan Fernando Alzate, Ana Civantos, Norman Balcázar, Juan José Pavón, Jean Paul Allain

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Statement of Purpose: Titanium (Ti) and its alloys (Ti6Al4V) are widely used in dentistry and orthopedics due to their excellent biological and mechanical properties. However, their osteointegration with the tissue is limited, which may lead to implant loosening and failure. One of the strategies to improve titanium bioactivity is through surface modification. This includes functionalizating the surface with growth factors like Bone Morphogenetic Protein-2 (BMP-2) that induce the differentiation of cells towards an osteogenic lineage, and/or changing the surface topography and/or chemistry using chemical and electrochemical methods such as etching and anodization, that can create micro and nanostructured surfaces1. However, these methods produce hazardous waste e.g. acids and bases. An alternative method is Direct Irradiation Synthesis (DIS), which is an advanced plasma synthesis technique that creates self-organized patterns of nanostructures on the surfaces. The aim of this study is to compare the surface properties and biological effect of microstructured surfaces produced by a patented chemical/electrochemical treatment to the nanopatterned surfaces produced by plasma irradiation, with or without BMP-2.

Original languageEnglish (US)
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - Jan 1 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

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  • Cite this

    Mesa, A., Montes, R., Patiño, E., Alzate, J. F., Civantos, A., Balcázar, N., Pavón, J. J., & Allain, J. P. (2019). Anodized/etched and dis treated ti surfaces to promote bone formation. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.