TY - GEN
T1 - Anodized/etched and dis treated ti surfaces to promote bone formation
AU - Mesa, Andrea
AU - Montes, Robinson
AU - Patiño, Edwin
AU - Alzate, Juan Fernando
AU - Civantos, Ana
AU - Balcázar, Norman
AU - Pavón, Juan José
AU - Allain, Jean Paul
N1 - Publisher Copyright:
© 2019 Omnipress - All rights reserved.
PY - 2019
Y1 - 2019
N2 - Statement of Purpose: Titanium (Ti) and its alloys (Ti6Al4V) are widely used in dentistry and orthopedics due to their excellent biological and mechanical properties. However, their osteointegration with the tissue is limited, which may lead to implant loosening and failure. One of the strategies to improve titanium bioactivity is through surface modification. This includes functionalizating the surface with growth factors like Bone Morphogenetic Protein-2 (BMP-2) that induce the differentiation of cells towards an osteogenic lineage, and/or changing the surface topography and/or chemistry using chemical and electrochemical methods such as etching and anodization, that can create micro and nanostructured surfaces1. However, these methods produce hazardous waste e.g. acids and bases. An alternative method is Direct Irradiation Synthesis (DIS), which is an advanced plasma synthesis technique that creates self-organized patterns of nanostructures on the surfaces. The aim of this study is to compare the surface properties and biological effect of microstructured surfaces produced by a patented chemical/electrochemical treatment to the nanopatterned surfaces produced by plasma irradiation, with or without BMP-2.
AB - Statement of Purpose: Titanium (Ti) and its alloys (Ti6Al4V) are widely used in dentistry and orthopedics due to their excellent biological and mechanical properties. However, their osteointegration with the tissue is limited, which may lead to implant loosening and failure. One of the strategies to improve titanium bioactivity is through surface modification. This includes functionalizating the surface with growth factors like Bone Morphogenetic Protein-2 (BMP-2) that induce the differentiation of cells towards an osteogenic lineage, and/or changing the surface topography and/or chemistry using chemical and electrochemical methods such as etching and anodization, that can create micro and nanostructured surfaces1. However, these methods produce hazardous waste e.g. acids and bases. An alternative method is Direct Irradiation Synthesis (DIS), which is an advanced plasma synthesis technique that creates self-organized patterns of nanostructures on the surfaces. The aim of this study is to compare the surface properties and biological effect of microstructured surfaces produced by a patented chemical/electrochemical treatment to the nanopatterned surfaces produced by plasma irradiation, with or without BMP-2.
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M3 - Conference contribution
AN - SCOPUS:85065443714
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
SP - 876
BT - Society for Biomaterials Annual Meeting and Exposition 2019
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -