Anisotropy of ultrasonic parameters in fresh rat skeletal muscle in vitro

Karen A. Topp, William D. O'Brien

Research output: Contribution to journalConference article

Abstract

The anisotropy of frequency dependent backscatter coefficient, attenuation, and speed of sound is assessed in fresh rat skeletal muscle within 5 hours post mortem. Excised rat semimembranosus and soleus muscles are measured in 37 °C Tyrode solution, with the muscle fibers at 90° and 45° orientations to the incident sound beam. Reflected and through transmission signals from either a 6 or 10 MHz focussed transducer give frequency dependent information in the 4-14 MHz range. The attenuation coefficient in each muscle is consistently 60±25% lower for propagation perpendicular to the fibers than at 45°, whereas speed of sound shows a much milder anisotropy (slightly faster for the 90° orientation) which is inconclusive within experimental error. The largest anisotropy is seen in the backscatter coefficient, most notably in the semimembranosus where the magnitude at 90° is over an order of magnitude greater than at 45°, with the frequency dependence in both cases giving a power law close to 2.

Original languageEnglish (US)
Pages (from-to)1369-1372
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume2
StatePublished - Dec 1 1998
EventProceedings of the 1998 International Ultrasonics Symposium - Sendai, Miyagi, Jpn
Duration: Oct 5 1998Oct 8 1998

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Fingerprint Dive into the research topics of 'Anisotropy of ultrasonic parameters in fresh rat skeletal muscle in vitro'. Together they form a unique fingerprint.

  • Cite this