Ancient human parallel lineages within North America contributed to a coastal expansion

C. L. Scheib, Hongjie Li, Tariq Desai, Vivian Link, Christopher Kendall, Genevieve Dewar, Peter William Griffith, Alexander Mörseburg, John R. Johnson, Amiee Potter, Susan L. Kerr, Phillip Endicott, John Lindo, Marc Haber, Yali Xue, Chris Tyler-Smith, Manjinder S. Sandhu, Joseph G. Lorenz, Tori D. Randall, Zuzana FaltyskovaLuca Pagani, Petr Danecek, Tamsin C. O’Connell, Patricia Martz, Alan S. Boraas, Brian F. Byrd, Alan Leventhal, Rosemary Cambra, Ronald Williamson, Louis Lesage, Brian Holguin, Ernestine Ygnacio De Soto, John Tommy Rosas, Mait Metspalu, Jay T. Stock, Andrea Manica, Aylwyn Scally, Daniel Wegmann, Ripan S. Malhi, Toomas Kivisild

Research output: Contribution to journalArticlepeer-review


Little is known regarding the first people to enter the Americas and their genetic legacy. Genomic analysis of the oldest human remains from the Americas showed a direct relationship between a Clovis-related ancestral population and all modern Central and South Americans as well as a deep split separating them from North Americans in Canada. We present 91 ancient human genomes from California and Southwestern Ontario and demonstrate the existence of two distinct ancestries in North America, which possibly split south of the ice sheets. A contribution from both of these ancestral populations is found in all modern Central and South Americans. The proportions of these two ancestries in ancient and modern populations are consistent with a coastal dispersal and multiple admixture events.

Original languageEnglish (US)
Pages (from-to)1024-1027
Number of pages4
Issue number6392
StatePublished - Jun 1 2018

ASJC Scopus subject areas

  • General


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