Three-dimensional tire-pavement contact loads of two truck tires-a new-generation wide-base tire (WBT) and a dual tire assembly (DTA)- were measured and analyzed. Extreme and typical values of tire inflation pressure (552, 690, 758, and 862 kPa) and tire loading (26, 35, 44, 62, and 79 kN) were considered in the experimental program. The measurements were performed with the stress-in-motion Mk IV system at the Council for Scientific and Industrial Research in South Africa. Peak values in three directions were compared, and the importance of tangential contact stresses was highlighted. In addition, characteristic variations of the measurements in the longitudinal, transverse, and vertical directions were identified. A function depending on two regression parameters, applied load, and distance along the contact length was proposed to represent the contact load in the vertical and transverse directions. An analysis was performed on the measurements to obtain the regression parameters, and a simplified procedure was proposed to determine tire-pavement contact loads. The contact area and contact length of the WBTs and the DTA were also compared.