Analysis of mAb reactive with the porcine SWC1

A. Saalmüller; B. Aasted; A. Canals; J. Dominguez; T. Goldman; J. K. Lunney; T. Pauly; M. D. Pescovitz; R. Pospisil; H. Salmon; J. Sinkora; A. Summerfield; I. Valpotic; J. S. Vizcaino; F. Zuckermann

doi:10.1016/0165-2427(94)90145-7

Analysis of mAb reactive with the porcine SWC1

A. Saalmüller, B. Aasted, A. Canals, J. Dominguez, T. Goldman, J. K. Lunney, T. Pauly, M. D. Pescovitz, R. Pospisil, H. Salmon, J. Sinkora, A. Summerfield, I. Valpotic, J. S. Vizcaino, F. Zuckermann

Research output: Contribution to journal › Article › peer-review

Abstract

Among 54 mAb determined to be reactive with porcine T lymphocytes and/or activation antigens, eight mAb (workshop Nos. 005, 031, 080, 091, 092, 093, 094 and 110) derived from different laboratories grouped together in the T11 cluster and were ordered into the SWC1. One mAb (No. 111) which belong also to this group was lost during the workshop. The SWC1 antigen is a molecule expressed on the majority of leukocytes, resting T lymphocytes, monocytes and granulocytes, but not on B lymphocytes. On T lymphocytes it is down-regulated after activation. The molecular mass of the antigen is unknown. Epitope analyses revealed that seven out of the nine mAb recognized similar epitopes on the SWC1 molecule.

Original language	English (US)
Pages (from-to)	255-258
Number of pages	4
Journal	Veterinary Immunology and Immunopathology
Volume	43
Issue number	1-3
DOIs	https://doi.org/10.1016/0165-2427(94)90145-7
State	Published - Oct 1994

ASJC Scopus subject areas

Immunology
General Veterinary

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10.1016/0165-2427(94)90145-7

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Saalmüller, A., Aasted, B., Canals, A., Dominguez, J., Goldman, T., Lunney, J. K., Pauly, T., Pescovitz, M. D., Pospisil, R., Salmon, H., Sinkora, J., Summerfield, A., Valpotic, I., Vizcaino, J. S., & Zuckermann, F. (1994). Analysis of mAb reactive with the porcine SWC1. Veterinary Immunology and Immunopathology, 43(1-3), 255-258. https://doi.org/10.1016/0165-2427(94)90145-7

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title = "Analysis of mAb reactive with the porcine SWC1",

abstract = "Among 54 mAb determined to be reactive with porcine T lymphocytes and/or activation antigens, eight mAb (workshop Nos. 005, 031, 080, 091, 092, 093, 094 and 110) derived from different laboratories grouped together in the T11 cluster and were ordered into the SWC1. One mAb (No. 111) which belong also to this group was lost during the workshop. The SWC1 antigen is a molecule expressed on the majority of leukocytes, resting T lymphocytes, monocytes and granulocytes, but not on B lymphocytes. On T lymphocytes it is down-regulated after activation. The molecular mass of the antigen is unknown. Epitope analyses revealed that seven out of the nine mAb recognized similar epitopes on the SWC1 molecule.",

author = "A. Saalm{\"u}ller and B. Aasted and A. Canals and J. Dominguez and T. Goldman and Lunney, {J. K.} and T. Pauly and Pescovitz, {M. D.} and R. Pospisil and H. Salmon and J. Sinkora and A. Summerfield and I. Valpotic and Vizcaino, {J. S.} and F. Zuckermann",

year = "1994",

month = oct,

doi = "10.1016/0165-2427(94)90145-7",

language = "English (US)",

volume = "43",

pages = "255--258",

journal = "Veterinary Immunology and Immunopathology",

issn = "0165-2427",

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TY - JOUR

T1 - Analysis of mAb reactive with the porcine SWC1

AU - Saalmüller, A.

AU - Aasted, B.

AU - Canals, A.

AU - Dominguez, J.

AU - Goldman, T.

AU - Lunney, J. K.

AU - Pauly, T.

AU - Pescovitz, M. D.

AU - Pospisil, R.

AU - Salmon, H.

AU - Sinkora, J.

AU - Summerfield, A.

AU - Valpotic, I.

AU - Vizcaino, J. S.

AU - Zuckermann, F.

PY - 1994/10

Y1 - 1994/10

N2 - Among 54 mAb determined to be reactive with porcine T lymphocytes and/or activation antigens, eight mAb (workshop Nos. 005, 031, 080, 091, 092, 093, 094 and 110) derived from different laboratories grouped together in the T11 cluster and were ordered into the SWC1. One mAb (No. 111) which belong also to this group was lost during the workshop. The SWC1 antigen is a molecule expressed on the majority of leukocytes, resting T lymphocytes, monocytes and granulocytes, but not on B lymphocytes. On T lymphocytes it is down-regulated after activation. The molecular mass of the antigen is unknown. Epitope analyses revealed that seven out of the nine mAb recognized similar epitopes on the SWC1 molecule.

AB - Among 54 mAb determined to be reactive with porcine T lymphocytes and/or activation antigens, eight mAb (workshop Nos. 005, 031, 080, 091, 092, 093, 094 and 110) derived from different laboratories grouped together in the T11 cluster and were ordered into the SWC1. One mAb (No. 111) which belong also to this group was lost during the workshop. The SWC1 antigen is a molecule expressed on the majority of leukocytes, resting T lymphocytes, monocytes and granulocytes, but not on B lymphocytes. On T lymphocytes it is down-regulated after activation. The molecular mass of the antigen is unknown. Epitope analyses revealed that seven out of the nine mAb recognized similar epitopes on the SWC1 molecule.

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SP - 255

EP - 258

JO - Veterinary Immunology and Immunopathology

JF - Veterinary Immunology and Immunopathology

IS - 1-3

ER -

Analysis of mAb reactive with the porcine SWC1

Abstract

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