Analyses of monoclonal antibodies reactive with porcine CD6

A. Saalmüller; B. Aasted; A. Canals; J. Dominguez; T. Goldman; J. K. Lunney; S. Maurer; T. Pauly; M. D. Pescovitz; R. Pospisil; H. Salmon; I. Trebichavsky; I. Valpotic; J. S. Vizcaino; E. Weiland; F. Zuckermann

doi:10.1016/0165-2427(94)90143-0

Analyses of monoclonal antibodies reactive with porcine CD6

A. Saalmüller, B. Aasted, A. Canals, J. Dominguez, T. Goldman, J. K. Lunney, S. Maurer, T. Pauly, M. D. Pescovitz, R. Pospisil, H. Salmon, I. Trebichavsky, I. Valpotic, J. S. Vizcaino, E. Weiland, F. Zuckermann

Research output: Contribution to journal › Article › peer-review

Abstract

Amongst the monoclonal antibodies (mAbs) submitted to the first porcine CD workshop, two mAbs (workshop numbers 055 and 120) could be identified to recognize the porcine CD6 analogue. Both mAbs seemed to be highly T-cell specific and showed neither reactivity with cells of the myeloic lineage nor with B lymphocytes. The observed molecular mass of the antigen precipitated by mAb 120 of 110 kDa confirmed this classification. Without molecular analyses of the antigen recognized by mAb 055, but similar staining pattern in FCM compared with 120, mAb 055 was allocated to the wCD6 subcluster.

Original language	English (US)
Pages (from-to)	243-247
Number of pages	5
Journal	Veterinary Immunology and Immunopathology
Volume	43
Issue number	1-3
DOIs	https://doi.org/10.1016/0165-2427(94)90143-0
State	Published - Oct 1994

ASJC Scopus subject areas

Immunology
General Veterinary

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10.1016/0165-2427(94)90143-0

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Saalmüller, A., Aasted, B., Canals, A., Dominguez, J., Goldman, T., Lunney, J. K., Maurer, S., Pauly, T., Pescovitz, M. D., Pospisil, R., Salmon, H., Trebichavsky, I., Valpotic, I., Vizcaino, J. S., Weiland, E., & Zuckermann, F. (1994). Analyses of monoclonal antibodies reactive with porcine CD6. Veterinary Immunology and Immunopathology, 43(1-3), 243-247. https://doi.org/10.1016/0165-2427(94)90143-0

Saalmüller, A, Aasted, B, Canals, A, Dominguez, J, Goldman, T, Lunney, JK, Maurer, S, Pauly, T, Pescovitz, MD, Pospisil, R, Salmon, H, Trebichavsky, I, Valpotic, I, Vizcaino, JS, Weiland, E & Zuckermann, F 1994, 'Analyses of monoclonal antibodies reactive with porcine CD6', Veterinary Immunology and Immunopathology, vol. 43, no. 1-3, pp. 243-247. https://doi.org/10.1016/0165-2427(94)90143-0

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abstract = "Amongst the monoclonal antibodies (mAbs) submitted to the first porcine CD workshop, two mAbs (workshop numbers 055 and 120) could be identified to recognize the porcine CD6 analogue. Both mAbs seemed to be highly T-cell specific and showed neither reactivity with cells of the myeloic lineage nor with B lymphocytes. The observed molecular mass of the antigen precipitated by mAb 120 of 110 kDa confirmed this classification. Without molecular analyses of the antigen recognized by mAb 055, but similar staining pattern in FCM compared with 120, mAb 055 was allocated to the wCD6 subcluster.",

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AU - Saalmüller, A.

AU - Aasted, B.

AU - Canals, A.

AU - Dominguez, J.

AU - Goldman, T.

AU - Lunney, J. K.

AU - Maurer, S.

AU - Pauly, T.

AU - Pescovitz, M. D.

AU - Pospisil, R.

AU - Salmon, H.

AU - Trebichavsky, I.

AU - Valpotic, I.

AU - Vizcaino, J. S.

AU - Weiland, E.

AU - Zuckermann, F.

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AB - Amongst the monoclonal antibodies (mAbs) submitted to the first porcine CD workshop, two mAbs (workshop numbers 055 and 120) could be identified to recognize the porcine CD6 analogue. Both mAbs seemed to be highly T-cell specific and showed neither reactivity with cells of the myeloic lineage nor with B lymphocytes. The observed molecular mass of the antigen precipitated by mAb 120 of 110 kDa confirmed this classification. Without molecular analyses of the antigen recognized by mAb 055, but similar staining pattern in FCM compared with 120, mAb 055 was allocated to the wCD6 subcluster.

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Analyses of monoclonal antibodies reactive with porcine CD6

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