Analyses of monoclonal antibodies reactive with porcine CD5

A. Saalmüller, B. Aasted, A. Canals, J. Dominguez, T. Goldman, J. K. Lunney, S. Maurer, M. D. Pescovitz, R. Pospisil, H. Salmon, A. Summerfield, H. Tlaskalova, I. Valpotic, J. S. Vizcaino, E. Weiland, F. Zuckermann

Research output: Contribution to journalArticlepeer-review

Abstract

Among all monoclonal antibodies (mAbs) analyzed in the first porcine CD workshop, six mAbs showed reactivity to the porcine CD5 antigen (workshop mAbs 067, 068, 069, 070, 071 and 119). Because of lack of immunoprecipitation studies for five (067, 068, 069, 070 and 071) out of the six mAbs, only one mAb (119) could be definitely characterized as mAb against the monomeric 63 kDa porcine CD5 antigen. The five other mAbs included in this cluster are characterized by an identical labelling pattern in FCM and competition of the CD5 epitope recognized by mAb 119. These mAbs were allocated to the wCD5 subcluster.

Original languageEnglish (US)
Pages (from-to)237-242
Number of pages6
JournalVeterinary Immunology and Immunopathology
Volume43
Issue number1-3
DOIs
StatePublished - Oct 1994

ASJC Scopus subject areas

  • Immunology
  • General Veterinary

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