Analgesic Efficacy of Tramadol Compared with Meloxicam in Ducks (Cairina moschata domestica) Evaluated by Ground-Reactive Forces

Ryan S. Bailey, Julie D. Sheldon, Matthew C Allender, Michael J. Adkesson, Sathya K. Chinnadurai

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to determine the efficacy of tramadol and meloxicam in an induced, temporary arthritis model in ducks as assessed by ground-reactive forces measured by a pressure-sensitive walkway (PSW) system. Twelve ducks (Cairina moschata domestica) were randomly separated into 3 equal groups of 4 birds each: water control, tramadol treatment, and meloxicam treatment. Baseline measurements were collected by having all ducks walk along a 3-m-long PSW in a custom-built corral before anesthesia and induction of arthritis. Arthritis was induced in all groups through injection, under anesthesia, of a 3% monosodium urate (MSU) solution into the intertarsal joint. One hour after MSU injection, birds were orally gavage fed 1 mL of tap water (control), tramadol (30 mg/kg), or meloxicam (1 mg/kg). After treatments, all ducks were reevaluated on the PSW at 1, 2, 3, 4, 8, and 24 hours post-MSU injection. The difference in maximum force was significantly greater in the control group than in both the tramadol-(P = .006) and meloxicam-treated (P = .03) individuals. Post hoc comparisons revealed differences between control and treated birds occurred only at the 3-and 4-hour time points after administration. No differences were found in the absolute difference in maximum force between tramadol-and meloxicam-treated birds at any time point (P > .05). Results of this study support the hypothesis that tramadol (30 mg/kg PO) and meloxicam (1 mg/kg PO) improve certain objective variables in an induced arthritis model in ducks. Our findings also support studies in other avian species that determined that both tramadol and meloxicam are effective analgesic drugs in some birds.

Original languageEnglish (US)
Pages (from-to)133-140
Number of pages8
JournalJournal of avian medicine and surgery
Volume33
Issue number2
DOIs
StatePublished - Jun 1 2019

Fingerprint

meloxicam
Cairina moschata
Tramadol
Ducks
analgesics
ducks
Analgesics
Birds
arthritis
Arthritis
Uric Acid
birds
injection
Pressure
Injections
anesthesia
Anesthesia
Tarsal Joints
Water
water birds

Keywords

  • Cairina moschata domestica
  • analgesia
  • arthritis
  • avian
  • duck
  • meloxicam
  • pressure-sensitive walkway
  • tramadol

ASJC Scopus subject areas

  • Small Animals

Cite this

Analgesic Efficacy of Tramadol Compared with Meloxicam in Ducks (Cairina moschata domestica) Evaluated by Ground-Reactive Forces. / Bailey, Ryan S.; Sheldon, Julie D.; Allender, Matthew C; Adkesson, Michael J.; Chinnadurai, Sathya K.

In: Journal of avian medicine and surgery, Vol. 33, No. 2, 01.06.2019, p. 133-140.

Research output: Contribution to journalArticle

Bailey, Ryan S. ; Sheldon, Julie D. ; Allender, Matthew C ; Adkesson, Michael J. ; Chinnadurai, Sathya K. / Analgesic Efficacy of Tramadol Compared with Meloxicam in Ducks (Cairina moschata domestica) Evaluated by Ground-Reactive Forces. In: Journal of avian medicine and surgery. 2019 ; Vol. 33, No. 2. pp. 133-140.
@article{f966a13d80e94126817800b769ab9847,
title = "Analgesic Efficacy of Tramadol Compared with Meloxicam in Ducks (Cairina moschata domestica) Evaluated by Ground-Reactive Forces",
abstract = "The purpose of this study was to determine the efficacy of tramadol and meloxicam in an induced, temporary arthritis model in ducks as assessed by ground-reactive forces measured by a pressure-sensitive walkway (PSW) system. Twelve ducks (Cairina moschata domestica) were randomly separated into 3 equal groups of 4 birds each: water control, tramadol treatment, and meloxicam treatment. Baseline measurements were collected by having all ducks walk along a 3-m-long PSW in a custom-built corral before anesthesia and induction of arthritis. Arthritis was induced in all groups through injection, under anesthesia, of a 3{\%} monosodium urate (MSU) solution into the intertarsal joint. One hour after MSU injection, birds were orally gavage fed 1 mL of tap water (control), tramadol (30 mg/kg), or meloxicam (1 mg/kg). After treatments, all ducks were reevaluated on the PSW at 1, 2, 3, 4, 8, and 24 hours post-MSU injection. The difference in maximum force was significantly greater in the control group than in both the tramadol-(P = .006) and meloxicam-treated (P = .03) individuals. Post hoc comparisons revealed differences between control and treated birds occurred only at the 3-and 4-hour time points after administration. No differences were found in the absolute difference in maximum force between tramadol-and meloxicam-treated birds at any time point (P > .05). Results of this study support the hypothesis that tramadol (30 mg/kg PO) and meloxicam (1 mg/kg PO) improve certain objective variables in an induced arthritis model in ducks. Our findings also support studies in other avian species that determined that both tramadol and meloxicam are effective analgesic drugs in some birds.",
keywords = "Cairina moschata domestica, analgesia, arthritis, avian, duck, meloxicam, pressure-sensitive walkway, tramadol",
author = "Bailey, {Ryan S.} and Sheldon, {Julie D.} and Allender, {Matthew C} and Adkesson, {Michael J.} and Chinnadurai, {Sathya K.}",
year = "2019",
month = "6",
day = "1",
doi = "10.1647/2018-364",
language = "English (US)",
volume = "33",
pages = "133--140",
journal = "Journal of Avian Medicine and Surgery",
issn = "1082-6742",
publisher = "Association of Avian Veterinarians",
number = "2",

}

TY - JOUR

T1 - Analgesic Efficacy of Tramadol Compared with Meloxicam in Ducks (Cairina moschata domestica) Evaluated by Ground-Reactive Forces

AU - Bailey, Ryan S.

AU - Sheldon, Julie D.

AU - Allender, Matthew C

AU - Adkesson, Michael J.

AU - Chinnadurai, Sathya K.

PY - 2019/6/1

Y1 - 2019/6/1

N2 - The purpose of this study was to determine the efficacy of tramadol and meloxicam in an induced, temporary arthritis model in ducks as assessed by ground-reactive forces measured by a pressure-sensitive walkway (PSW) system. Twelve ducks (Cairina moschata domestica) were randomly separated into 3 equal groups of 4 birds each: water control, tramadol treatment, and meloxicam treatment. Baseline measurements were collected by having all ducks walk along a 3-m-long PSW in a custom-built corral before anesthesia and induction of arthritis. Arthritis was induced in all groups through injection, under anesthesia, of a 3% monosodium urate (MSU) solution into the intertarsal joint. One hour after MSU injection, birds were orally gavage fed 1 mL of tap water (control), tramadol (30 mg/kg), or meloxicam (1 mg/kg). After treatments, all ducks were reevaluated on the PSW at 1, 2, 3, 4, 8, and 24 hours post-MSU injection. The difference in maximum force was significantly greater in the control group than in both the tramadol-(P = .006) and meloxicam-treated (P = .03) individuals. Post hoc comparisons revealed differences between control and treated birds occurred only at the 3-and 4-hour time points after administration. No differences were found in the absolute difference in maximum force between tramadol-and meloxicam-treated birds at any time point (P > .05). Results of this study support the hypothesis that tramadol (30 mg/kg PO) and meloxicam (1 mg/kg PO) improve certain objective variables in an induced arthritis model in ducks. Our findings also support studies in other avian species that determined that both tramadol and meloxicam are effective analgesic drugs in some birds.

AB - The purpose of this study was to determine the efficacy of tramadol and meloxicam in an induced, temporary arthritis model in ducks as assessed by ground-reactive forces measured by a pressure-sensitive walkway (PSW) system. Twelve ducks (Cairina moschata domestica) were randomly separated into 3 equal groups of 4 birds each: water control, tramadol treatment, and meloxicam treatment. Baseline measurements were collected by having all ducks walk along a 3-m-long PSW in a custom-built corral before anesthesia and induction of arthritis. Arthritis was induced in all groups through injection, under anesthesia, of a 3% monosodium urate (MSU) solution into the intertarsal joint. One hour after MSU injection, birds were orally gavage fed 1 mL of tap water (control), tramadol (30 mg/kg), or meloxicam (1 mg/kg). After treatments, all ducks were reevaluated on the PSW at 1, 2, 3, 4, 8, and 24 hours post-MSU injection. The difference in maximum force was significantly greater in the control group than in both the tramadol-(P = .006) and meloxicam-treated (P = .03) individuals. Post hoc comparisons revealed differences between control and treated birds occurred only at the 3-and 4-hour time points after administration. No differences were found in the absolute difference in maximum force between tramadol-and meloxicam-treated birds at any time point (P > .05). Results of this study support the hypothesis that tramadol (30 mg/kg PO) and meloxicam (1 mg/kg PO) improve certain objective variables in an induced arthritis model in ducks. Our findings also support studies in other avian species that determined that both tramadol and meloxicam are effective analgesic drugs in some birds.

KW - Cairina moschata domestica

KW - analgesia

KW - arthritis

KW - avian

KW - duck

KW - meloxicam

KW - pressure-sensitive walkway

KW - tramadol

UR - http://www.scopus.com/inward/record.url?scp=85066143881&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85066143881&partnerID=8YFLogxK

U2 - 10.1647/2018-364

DO - 10.1647/2018-364

M3 - Article

C2 - 31251500

AN - SCOPUS:85066143881

VL - 33

SP - 133

EP - 140

JO - Journal of Avian Medicine and Surgery

JF - Journal of Avian Medicine and Surgery

SN - 1082-6742

IS - 2

ER -