An investigation of multivariable models for human response to anesthesia

Hui Hung Lin; Carolyn Beck; Joseph Nedumgottil; Marc Bloom

doi:10.1109/CDC.2001.980215

An investigation of multivariable models for human response to anesthesia

Hui Hung Lin, Carolyn Beck, Joseph Nedumgottil, Marc Bloom

Research output: Contribution to journal › Article › peer-review

Abstract

The use of linear multi-input multi-output (MIMO) models was investigated to describe the relations between input anesthetic agents and surgical stimuli to the patient endpoint variables of heart rate, mean arterial pressure, and electroencephalography (EEG) signals. Comparison of the linear time-invariant model (LTI) was done with the pharmacokinetic-pharmacodynamic (PK-PD) models. The differences in measured and predicted output responses were also evaluated for the LTI and PD models.

Original language	English (US)
Pages (from-to)	867-868
Number of pages	2
Journal	Proceedings of the IEEE Conference on Decision and Control
Volume	1
DOIs	https://doi.org/10.1109/CDC.2001.980215
State	Published - 2001

ASJC Scopus subject areas

Control and Systems Engineering
Modeling and Simulation
Control and Optimization

Access to Document

10.1109/CDC.2001.980215

Cite this

@article{45e4ff3180e74b24bbf45eb4c0a39e34,

title = "An investigation of multivariable models for human response to anesthesia",

abstract = "The use of linear multi-input multi-output (MIMO) models was investigated to describe the relations between input anesthetic agents and surgical stimuli to the patient endpoint variables of heart rate, mean arterial pressure, and electroencephalography (EEG) signals. Comparison of the linear time-invariant model (LTI) was done with the pharmacokinetic-pharmacodynamic (PK-PD) models. The differences in measured and predicted output responses were also evaluated for the LTI and PD models.",

author = "Lin, {Hui Hung} and Carolyn Beck and Joseph Nedumgottil and Marc Bloom",

year = "2001",

doi = "10.1109/CDC.2001.980215",

language = "English (US)",

volume = "1",

pages = "867--868",

journal = "Proceedings of the IEEE Conference on Decision and Control",

issn = "0191-2216",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

}

TY - JOUR

T1 - An investigation of multivariable models for human response to anesthesia

AU - Lin, Hui Hung

AU - Beck, Carolyn

AU - Nedumgottil, Joseph

AU - Bloom, Marc

PY - 2001

Y1 - 2001

N2 - The use of linear multi-input multi-output (MIMO) models was investigated to describe the relations between input anesthetic agents and surgical stimuli to the patient endpoint variables of heart rate, mean arterial pressure, and electroencephalography (EEG) signals. Comparison of the linear time-invariant model (LTI) was done with the pharmacokinetic-pharmacodynamic (PK-PD) models. The differences in measured and predicted output responses were also evaluated for the LTI and PD models.

AB - The use of linear multi-input multi-output (MIMO) models was investigated to describe the relations between input anesthetic agents and surgical stimuli to the patient endpoint variables of heart rate, mean arterial pressure, and electroencephalography (EEG) signals. Comparison of the linear time-invariant model (LTI) was done with the pharmacokinetic-pharmacodynamic (PK-PD) models. The differences in measured and predicted output responses were also evaluated for the LTI and PD models.

UR - http://www.scopus.com/inward/record.url?scp=0035710604&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035710604&partnerID=8YFLogxK

U2 - 10.1109/CDC.2001.980215

DO - 10.1109/CDC.2001.980215

M3 - Article

AN - SCOPUS:0035710604

VL - 1

SP - 867

EP - 868

JO - Proceedings of the IEEE Conference on Decision and Control

JF - Proceedings of the IEEE Conference on Decision and Control

SN - 0191-2216

ER -

An investigation of multivariable models for human response to anesthesia

Abstract

ASJC Scopus subject areas

Access to Document

Other links

Fingerprint

Cite this