Abstract
The use of linear multi-input multi-output (MIMO) models was investigated to describe the relations between input anesthetic agents and surgical stimuli to the patient endpoint variables of heart rate, mean arterial pressure, and electroencephalography (EEG) signals. Comparison of the linear time-invariant model (LTI) was done with the pharmacokinetic-pharmacodynamic (PK-PD) models. The differences in measured and predicted output responses were also evaluated for the LTI and PD models.
Original language | English (US) |
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Pages (from-to) | 867-868 |
Number of pages | 2 |
Journal | Proceedings of the IEEE Conference on Decision and Control |
Volume | 1 |
DOIs | |
State | Published - 2001 |
ASJC Scopus subject areas
- Control and Systems Engineering
- Modeling and Simulation
- Control and Optimization