An integrated platform for surface forces measurements and fluorescence correlation spectroscopy

Ashis Mukhopadhyay, Jiang Zhao, Sung Chul Bae, Steve Granick

Research output: Contribution to journalArticlepeer-review

Abstract

The measurement of the diffusion of dilute fluorophores in molecularly thin liquid films within a surface forces apparatus (SFA) was described. A modification of the traditional SFA allows one to combine nanorheology with the single molecule sensitive technique of fluorescence correlation spectroscopy. The diffusion coefficient was found to decrease by 2 orders of magnitude under confinement.

Original languageEnglish (US)
Pages (from-to)3067-3072
Number of pages6
JournalReview of Scientific Instruments
Volume74
Issue number6
DOIs
StatePublished - Jun 2003

ASJC Scopus subject areas

  • Instrumentation

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