An extended diffraction-enhanced imaging method for implementing multiple-image radiography

Cheng Ying Chou, Mark A. Anastasio, Jovan G. Brankov, Miles N. Wernick, Eric M. Brey, Dean M. Connor, Zhong Zhong

Research output: Contribution to journalArticlepeer-review


Diffraction-enhanced imaging (DEI) is an analyser-based x-ray imaging method that produces separate images depicting the projected x-ray absorption and refractive properties of an object. Because the imaging model of DEI does not account for ultra-small-angle x-ray scattering (USAXS), the images produced in DEI can contain artefacts and inaccuracies in medical imaging applications. In this work, we investigate an extended DEI method for concurrent reconstruction of three images that depict an object's projected x-ray absorption, refraction and USAXS properties. The extended DEI method can be viewed as an implementation of the recently proposed multiple-image radiography paradigm. Validation studies are conducted by use of computer-simulated and synchrotron measurement data.

Original languageEnglish (US)
Article number011
Pages (from-to)1923-1945
Number of pages23
JournalPhysics in medicine and biology
Issue number7
StatePublished - Apr 7 2007
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering
  • Physics and Astronomy (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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