TY - JOUR
T1 - An evaluation of the genotoxic properties of insecticides following plant and animal activation
AU - Gentile, James M.
AU - Gentile, Glenda J.
AU - Bultman, Judy
AU - Sechriest, Robert
AU - Wagner, Elizabeth D.
AU - Plewa, Michael J.
N1 - Funding Information:
The authors gratefully acknowledge the technical assistance of L. Overton, L. Sunderlin, L. Frasch, C. Wells, and M.L. Ho. This research was supported by U S. EPA Contract 68-02-2704.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1982/3
Y1 - 1982/3
N2 - Commercial and technical grades of 10 insecticides were evaluated for genotoxicity with Salmonella typhimurium and Saccharomyces cerevisiae directly and following plant and animal activation. Field-grade formulations of each insecticide were also tested for mutations at the waxy (wx) locus in Zea mays in situ. Carbofuran, chloropyrifos, curacron, metham and phorate were negative in all assays. Ethoprop and terbufos were each positive in 1 assay, and chlordane, fonofos and heptachlor were each positive in 2 assays. Fonofos and terbufos were positive directly and following animal activation while chlordane and heptachlor were positive following both plant and animal activation. Chlordane, ethoprop, and heptachlor were positive in Z. mays.
AB - Commercial and technical grades of 10 insecticides were evaluated for genotoxicity with Salmonella typhimurium and Saccharomyces cerevisiae directly and following plant and animal activation. Field-grade formulations of each insecticide were also tested for mutations at the waxy (wx) locus in Zea mays in situ. Carbofuran, chloropyrifos, curacron, metham and phorate were negative in all assays. Ethoprop and terbufos were each positive in 1 assay, and chlordane, fonofos and heptachlor were each positive in 2 assays. Fonofos and terbufos were positive directly and following animal activation while chlordane and heptachlor were positive following both plant and animal activation. Chlordane, ethoprop, and heptachlor were positive in Z. mays.
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U2 - 10.1016/0165-1218(82)90161-6
DO - 10.1016/0165-1218(82)90161-6
M3 - Article
C2 - 7043246
AN - SCOPUS:0020040822
SN - 0165-1218
VL - 101
SP - 19
EP - 29
JO - Mutation Research/Genetic Toxicology
JF - Mutation Research/Genetic Toxicology
IS - 1
ER -