Abstract
The mercury(II)-catalyzed cyclization of 4-pentynoic acid proceeds efficiently to give γ-methylene-γ-butyrolac-tone (α'-angelicalactone). The enolate of this lactone reacts with 11-dodecenal producing separable diastereomeric β-hydroxylactones. The corresponding methanesulfonate derivatives undergo partially selective elimination to afford deoxyobtusilactone and deoxyisoobtusilactone.
Original language | English (US) |
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Pages (from-to) | 560-564 |
Number of pages | 5 |
Journal | Journal of Organic Chemistry |
Volume | 43 |
Issue number | 4 |
DOIs | |
State | Published - 1978 |
ASJC Scopus subject areas
- Organic Chemistry