TY - GEN
T1 - An efficient permutation approach for classical and bioequivalence hypothesis testing of biomedical shape study
AU - Zhou, Chunxiao
AU - Wang, Michelle Yongmei
PY - 2008
Y1 - 2008
N2 - A new statistical permutation analysis method is presented in this paper to efficiently and accurately localize regionally specific shape differences between groups of 3D biomedical images. It can improve the system's efficiency by approximating the permutation distribution of the test statistic with Pearson distribution series. This procedure involves the calculation of the first four moments of the permutation distribution, which are derived theoretically and analytically without any permutation. Furthermore, bioequivalence testing aims for practical significances between the two groups that are statistically significant with the shape differences larger than a desired threshold. Experimental results based on both classical and bioequivalence hypothesis tests using simulated data and real biomedical images are presented to demonstrate the advantages of the proposed approach.
AB - A new statistical permutation analysis method is presented in this paper to efficiently and accurately localize regionally specific shape differences between groups of 3D biomedical images. It can improve the system's efficiency by approximating the permutation distribution of the test statistic with Pearson distribution series. This procedure involves the calculation of the first four moments of the permutation distribution, which are derived theoretically and analytically without any permutation. Furthermore, bioequivalence testing aims for practical significances between the two groups that are statistically significant with the shape differences larger than a desired threshold. Experimental results based on both classical and bioequivalence hypothesis tests using simulated data and real biomedical images are presented to demonstrate the advantages of the proposed approach.
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U2 - 10.1109/BMEI.2008.192
DO - 10.1109/BMEI.2008.192
M3 - Conference contribution
AN - SCOPUS:51649121128
SN - 9780769531182
T3 - BioMedical Engineering and Informatics: New Development and the Future - Proceedings of the 1st International Conference on BioMedical Engineering and Informatics, BMEI 2008
SP - 737
EP - 741
BT - BioMedical Engineering and Informatics
T2 - BioMedical Engineering and Informatics: New Development and the Future - 1st International Conference on BioMedical Engineering and Informatics, BMEI 2008
Y2 - 27 May 2008 through 30 May 2008
ER -