An efficient characterization of complex-balanced, detailed-balanced, and weakly reversible systems

Gheorghe Craciun, Jiaxin Jin, Polly Y. Yu

Research output: Contribution to journalArticlepeer-review

Abstract

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary difierential equations, arising from a reaction network. Such dynamical systems can be generated by many difierent reaction networks. On the other hand, networks with special properties (such as reversibility or weak reversibility) are known or conjectured to give rise to dynamical systems that have special properties: Existence of positive steady states, persistence, permanence, and (for well-chosen parameters) complex balancing or detailed balancing. These last two are related to thermodynamic equilibrium, and therefore the positive steady states are unique and stable. We describe a computationally efficient characterization of polynomial or power-law dynamical systems that can be obtained as complex-balanced, detailed-balanced, weakly reversible, and reversible mass-action systems.

Original languageEnglish (US)
Pages (from-to)183-205
Number of pages23
JournalSIAM Journal on Applied Mathematics
Volume80
Issue number1
DOIs
StatePublished - 2020
Externally publishedYes

Keywords

  • Complex-balanced systems
  • Mass-action kinetics
  • Network identifiability
  • Polynomial dynamical systems
  • Reaction networks
  • Ux systems

ASJC Scopus subject areas

  • Applied Mathematics

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