TY - JOUR
T1 - An efficient characterization of complex-balanced, detailed-balanced, and weakly reversible systems
AU - Craciun, Gheorghe
AU - Jin, Jiaxin
AU - Yu, Polly Y.
N1 - Publisher Copyright:
© 2020 Society for Industrial and Applied Mathematics.
PY - 2020
Y1 - 2020
N2 - Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary difierential equations, arising from a reaction network. Such dynamical systems can be generated by many difierent reaction networks. On the other hand, networks with special properties (such as reversibility or weak reversibility) are known or conjectured to give rise to dynamical systems that have special properties: Existence of positive steady states, persistence, permanence, and (for well-chosen parameters) complex balancing or detailed balancing. These last two are related to thermodynamic equilibrium, and therefore the positive steady states are unique and stable. We describe a computationally efficient characterization of polynomial or power-law dynamical systems that can be obtained as complex-balanced, detailed-balanced, weakly reversible, and reversible mass-action systems.
AB - Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary difierential equations, arising from a reaction network. Such dynamical systems can be generated by many difierent reaction networks. On the other hand, networks with special properties (such as reversibility or weak reversibility) are known or conjectured to give rise to dynamical systems that have special properties: Existence of positive steady states, persistence, permanence, and (for well-chosen parameters) complex balancing or detailed balancing. These last two are related to thermodynamic equilibrium, and therefore the positive steady states are unique and stable. We describe a computationally efficient characterization of polynomial or power-law dynamical systems that can be obtained as complex-balanced, detailed-balanced, weakly reversible, and reversible mass-action systems.
KW - Complex-balanced systems
KW - Mass-action kinetics
KW - Network identifiability
KW - Polynomial dynamical systems
KW - Reaction networks
KW - Ux systems
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U2 - 10.1137/19M1244494
DO - 10.1137/19M1244494
M3 - Article
AN - SCOPUS:85075686776
SN - 0036-1399
VL - 80
SP - 183
EP - 205
JO - SIAM Journal on Applied Mathematics
JF - SIAM Journal on Applied Mathematics
IS - 1
ER -