An advanced photoacoustic tomography system based on a ring geometry design

Suhail Alshahrani, Yan Yan, Ivan Avrutsky, Eugene Malyarenko, Mark Anastasio, Mohammad Mehrmohammadi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Among various types of cancer, breast cancer is considered to be the most common that affects thousands of women all over the world. Several imaging tools are being used for breast cancer detection and diagnosis. Mammography and B-mode ultrasound (US) are the primary screening tools for breast lesions. However, mammography is limited with low sensitivity especially in women with dense breasts, who appear to be at higher risk of breast cancer. Additionally, the B-mode US suffers from low specificity in the differential diagnosis of breast lesions. Therefore, it is clinically significant to develop screening techniques that could eliminate previous limitations. Photoacoustic (PA) has been showing potential for early stage detection and staging breast cancer due to its unique abilities to acquire functional and molecular information of the breast lesions. We have developed an optimized US and PA tomography system, which uses custom designed all reflective based optics to create an omnidirectional ring-shaped beam to illuminate a cross-section of the breast tissue and acquire thegenerated acoustic waves by using a full-ring US transducer. The developed PA tomography (PAT) system can potentially make a more uniform illumination of the breast tissue and more importantly enhance the imaging depth. In this study, development of the full-ring illumination and the results of our initial feasibility US/PA tests are presented.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2018
Subtitle of host publicationUltrasonic Imaging and Tomography
EditorsNeb Duric, Brett C. Byram
PublisherSPIE
ISBN (Electronic)9781510616493
DOIs
StatePublished - Jan 1 2018
Externally publishedYes
EventMedical Imaging 2018: Ultrasonic Imaging and Tomography - Houston, United States
Duration: Feb 13 2018Feb 15 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10580
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2018: Ultrasonic Imaging and Tomography
Country/TerritoryUnited States
CityHouston
Period2/13/182/15/18

Keywords

  • Omnidirectional
  • Photoacoustic
  • Ring illumination
  • Tomography
  • Ultrasound

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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