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Amphotericin forms an extramembranous and fungicidal sterol sponge
Thomas M. Anderson
, Mary C. Clay
, Alexander G. Cioffi
, Katrina A. Diaz
, Grant S. Hisao
, Marcus D. Tuttle
, Andrew J. Nieuwkoop
, Gemma Comellas
, Nashrah Maryum
, Shu Wang
, Brice E. Uno
, Erin L. Wildeman
, Tamir Gonen
, Chad M. Rienstra
,
Martin D. Burke
Chemistry
Biochemistry
Carle Illinois College of Medicine
Beckman Institute for Advanced Science and Technology
Carl R. Woese Institute for Genomic Biology
Biomedical and Translational Sciences
Siebel Center for Design
Center for Global Studies
Research output
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peer-review
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Keyphrases
Sterols
100%
Amphotericin B
100%
Lipid Bilayer
33%
Cytocidal
33%
Small Molecules
16%
Lipids
16%
Human Cells
16%
Life-threatening
16%
Polyfunctional
16%
First Derivative
16%
Mechanistic Understanding
16%
Ergosterol
16%
Antimicrobial
16%
Antimicrobial Activity
16%
Therapeutic Index
16%
Fungal Infection
16%
Ion Channel Model
16%
Microbial Resistance
16%
Permeabilizing Activity
16%
Lines of Defense
16%
Last Line
16%
Biochemistry, Genetics and Molecular Biology
Lipid Bilayer
100%
Sterol
100%
Lipid
50%
Small Molecule
50%
Antimicrobial Activity
50%
Ion Channel
50%
Ergosterol
50%
Immunology and Microbiology
Lipid Bilayer
100%
Antimicrobial Activity
50%
Human Cell
50%
Antimicrobial Resistance
50%